Journal article
Nearly neutrality and the evolution of codon usage bias in eukaryotic genomes
Genetics, Vol.178(4), pp.2429-2432
2008
Abstract
Here I show that the mean codon usage bias of a genome, and of the lowly expressed genes in a genome, is largely similar across eukaryotes ranging from unicellular protists to vertebrates. Conversely, this bias in housekeeping genes and in highly expressed genes has a remarkable inverse relationship with species generation time that varies by more than four orders of magnitude. The relevance of these results to the nearly neutral theory of molecular evolution is discussed. Copyright © 2008 by the Genetics Society of America.
Details
- Title
- Nearly neutrality and the evolution of codon usage bias in eukaryotic genomes
- Authors
- Sankar Subramanian (Author) - Massey University, New Zealand
- Publication details
- Genetics, Vol.178(4), pp.2429-2432
- Publisher
- Genetics Society of America
- Date published
- 2008
- DOI
- 10.1534/genetics.107.086405
- ISSN
- 0016-6731
- Organisation Unit
- School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99450549402621
- Output Type
- Journal article
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