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Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.
Journal article   Peer reviewed

Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.

Larissa Buedenbender, Tanja Grkovic, Sandra Duffy, D Ipek Kurtboke, Vicky M Avery and Anthony R Carroll
Tetrahedron Letters, Vol.57(52), pp.5893-5895
2016
url
https://doi.org/10.1016/j.tetlet.2016.11.071View
Published Version

Abstract

marine streptomyces species naseseazines diketopiperazines anti-plasmodial
A new dimeric diketopiperazine, naseseazine C, and the known naseseazines A and B were isolated from solid culture extracts of an Australian marine sediment derived Streptomyces species. Naseseazine C displayed a new C-6′/C-3 linkage between the two diketopiperazine subunits and showed moderate activity against the chloroquine-sensitive malaria parasite, Plasmodium falciparum (3D7 strain).

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Chemistry, Organic

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