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Molecular interactions in collagen and chitosan blends
Journal article   Peer reviewed

Molecular interactions in collagen and chitosan blends

A Sionkowska, M Wisniewski, J Skopinska, Craig J Kennedy and Tim J Wess
Biomaterials, Vol.25(5), pp.795-801
2004
url
https://doi.org/10.1016/S0142-9612(03)00595-7View
Published Version

Abstract

Collagen Chitosan FTIR XRD structure viscometry gelatin
Molecular interactions between collagen and chitosan (CC) have the potential to produce biocomposites with novel properties. We have characterised the molecular interactions in CC complexes by viscometry, wide angle X-ray scattering and Fourier transform infrared spectroscopy. It was found that CC are miscible at the molecular level and exhibit interactions between the components; X-ray diffraction of CC blends indicate that the collagen helix structure is lost in CC films with increasing chitosan content. Non-linear viscometic behaviour with decreasing chitosan content is interpreted as evidence of a third structural phase formed as a complex of CC. The blending of collagen with chitosan gives the possibility of producing new bespoke materials for potential biomedical applications. © 2003 Elsevier Ltd. All rights reserved.

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Engineering, Biomedical
Materials Science, Biomaterials
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