Microevolution of Burkholderia pseudomallei during an acute infection

D Limmathurotsakul; M T G Holden; P Coupland; Erin P Price; N Chantratita; V Wuthiekanun; P Amornchai; J Parkhill; S J Peacock

doi:10.1128/JCM.01219-14

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Microevolution of Burkholderia pseudomallei during an acute infection

Journal article

Open access

Peer reviewed

Microevolution of Burkholderia pseudomallei during an acute infection

D Limmathurotsakul, M T G Holden, P Coupland, Erin P Price, N Chantratita, V Wuthiekanun, P Amornchai, J Parkhill and S J Peacock

Journal of Clinical Microbiology, Vol.52(9), pp.3418-3421

2014

DOI: https://doi.org/10.1128/JCM.01219-14

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Abstract

We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei after inoculation and systemic spread. Copyright © 2014 Limmathurotsakul et al.

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Title: Microevolution of Burkholderia pseudomallei during an acute infection
Authors: D Limmathurotsakul (Author) - Mahidol University, Thailand
M T G Holden (Author) - Mahidol University, Thailand
P Coupland (Author) - Mahidol University, Thailand
Erin P Price (Author) - Menzies School of Health Research
N Chantratita (Author) - Mahidol University, Thailand
V Wuthiekanun (Author) - Mahidol University, Thailand
P Amornchai (Author) - Mahidol University, Thailand
J Parkhill (Author) - Mahidol University, Thailand
S J Peacock (Author) - Cambridge University, United Kingdom
Publication details: Journal of Clinical Microbiology, Vol.52(9), pp.3418-3421
Publisher: American Society for Microbiology
Date published: 2014
DOI: 10.1128/JCM.01219-14
ISSN: 0095-1137
Copyright note: Copyright © 2014 American Society for Microbiology. Reproduced here in accordance with the publisher's copyright policy.
Organisation Unit: University of the Sunshine Coast, Queensland; Centre for Bioinnovation
Language: English
Record Identifier: 99451148202621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Microbiology

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