Journal article
Microbial biotransformation as a source of chemical diversity in cane toad steroid toxins
Bioorganic & Medicinal Chemistry Letters, Vol.19(6), pp.1790-1792
2009
Abstract
The cane toad is an invasive pest that is rapidly colonising northern Australia. The cane toad parotoid gland secretes cardiotoxic steroids (bufadienolides) that are poisoning native predator species. This study reveals bufadienolide diversity within the secretions of Australian cane toads is different to cane toads from overseas, being far more structurally diverse than previously assumed. It is proposed that this variation is mediated by in situ bacterial biotransformation.
Details
- Title
- Microbial biotransformation as a source of chemical diversity in cane toad steroid toxins
- Authors
- R Andrew Hayes (Author) - University of QueenslandA M Piggott (Author) - University of QueenslandK Dalle (Author) - University of QueenslandR J Capon (Author) - University of Queensland
- Publication details
- Bioorganic & Medicinal Chemistry Letters, Vol.19(6), pp.1790-1792
- Publisher
- Pergamon
- Date published
- 2009
- DOI
- 10.1016/j.bmcl.2009.01.064
- ISSN
- 0960-894X
- Organisation Unit
- University of the Sunshine Coast, Queensland; Forest Industries Research Centre; Forest Research Institute
- Language
- English
- Record Identifier
- 99449290602621
- Output Type
- Journal article
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InCites Highlights
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- Web Of Science research areas
- Chemistry, Medicinal
- Chemistry, Organic
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Source: InCites