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Medium Scale Integration of Molecular Logic Gates in an Automaton
Journal article   Peer reviewed

Medium Scale Integration of Molecular Logic Gates in an Automaton

Joanne Macdonald, Y Li, M Sutovic, H Lederman, K Pendri, W Lu, B L Andrews, D Stefanovic and M N Stojanovic
Nano Letters, Vol.6(11), p.2598–2603
2006
url
https://doi.org/10.1021/nl0620684View
Published Version

Abstract

The assembly of molecular automata that perform increasingly complex tasks, such as game playing, presents an unbiased test of molecular computation. We now report a second-generation deoxyribozyme-based automaton, MAYA-II, which plays a complete game of tic-tac-toe according to a perfect strategy. In silicon terminology, MAYA-II represents the first "medium-scale integrated molecular circuit", integrating 128 deoxyribozyme-based logic gates, 32 input DNA molecules, and 8 two-channel fluorescent outputs across 8 wells.

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Collaboration types
Domestic collaboration
Web Of Science research areas
Chemistry, Multidisciplinary
Chemistry, Physical
Materials Science, Multidisciplinary
Nanoscience & Nanotechnology
Physics, Applied
Physics, Condensed Matter

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