Mapping the primary motor cortex in healthy subjects and patients with peri-rolandic brain lesions before neurosurgery

E M Berntsen; P Samuelsen; Jim Lagopoulos; I A Rasmussen Jr; A K Håberg; O Haraldseth

doi:10.1179/016164108X323753

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Mapping the primary motor cortex in healthy subjects and patients with peri-rolandic brain lesions before neurosurgery

Journal article

Peer reviewed

Mapping the primary motor cortex in healthy subjects and patients with peri-rolandic brain lesions before neurosurgery

E M Berntsen, P Samuelsen, Jim Lagopoulos, I A Rasmussen Jr, A K Håberg and O Haraldseth

Neurological Research, Vol.30(9), pp.968-973

2008

DOI: https://doi.org/10.1179/016164108X323753

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Abstract

BOLD fMRI

finger tapping

functional neuronavigation

motor cortex

pre-operative planning

Objective: The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for preoperative planning and functional neuronavigation. Method: Twelve male and four female control subjects were recruited for this study which examined six different motor tasks. Finger-, tongue-, lip- and toe-movements, as well as isometric upper arm- and thigh-contraction tasks were conducted during separate scans on a 3 T MRI scanner. Furthermore, patients that previously had undergone similar motor tasks were reviewed, to evaluate whether this set of tasks was able to be adopted for use in a population of patients with brain lesions. Results: The results of this study indicated that the finger-, toe- and tongue-motor tasks were the most robust in identifying their respective primary motor area. Moreover, all three tasks activated regions at regular intervals along the convexity of the hemisphere, making it possible to functionally delineate the primary motor cortex in both healthy subjects and patients. Discussion: The motor tasks described in this study (toe, finger and tongue) were effective at localizing the primary motor cortex for the purposes of neurosurgical planning. These three tasks produced the highest success rate and resulted in activations at regular intervals along the convexity of the hemisphere, allowing the delineation of the entire motor strip even in the presence of edema and anatomical distortions. © 2008 W. S. Maney & Son Ltd.

Details

Title: Mapping the primary motor cortex in healthy subjects and patients with peri-rolandic brain lesions before neurosurgery
Authors: E M Berntsen (Author) - Norwegian University of Science and Technology (NTNU), Norway
P Samuelsen (Author) - Norwegian University of Science and Technology (NTNU), Norway
Jim Lagopoulos (Author) - University of Sydney
I A Rasmussen Jr (Author) - University of Oslo, Norway
A K Håberg (Author) - Norwegian University of Science and Technology (NTNU), Norway
O Haraldseth (Author) - Norwegian University of Science and Technology (NTNU), Norway
Publication details: Neurological Research, Vol.30(9), pp.968-973
Publisher: Taylor & Francis Ltd.
Date published: 2008
DOI: 10.1179/016164108X323753
ISSN: 0161-6412
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99449305402621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Clinical Neurology; Neurosciences

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