Management of depression in patients with coronary artery disease: A systematic review

Wole Akosile; Babangida Tiyatiye; David Colquhoun; Ross Young

doi:10.1016/j.ajp.2023.103534

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Management of depression in patients with coronary artery disease: A systematic review

Journal article

Open access

Peer reviewed

Management of depression in patients with coronary artery disease: A systematic review

Wole Akosile, Babangida Tiyatiye, David Colquhoun and Ross Young

Asian Journal of Psychiatry, Vol.83, pp.1-15

2023

DOI: https://doi.org/10.1016/j.ajp.2023.103534

PMID: 36871435

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Abstract

CAD

Cardiovascular disease

Coronary artery disease

Depression

MDD

Psychopharmacology

Psychotherapy

Depression is an independent risk factor for coronary artery disease (CAD). Both illnesses contribute significantly to the global burden of disease. This systematic literature review examines treatment interventions for CAD patients with comorbid depression. We systematically reviewed The Cochrane Library, MEDLINE, EMBASE, PsycINFO, PUBMED, CINAHL and the ISRCTN Registry for English language randomised control trials investigating treatment interventions for depression in adults with CAD and comorbid depression. Data extracted included author name(s), year published, number of participants, enrolment criteria, depression definition/measures (standardised interviews, rating scales), description of control arms and interventions (psychotherapy and/or medications), randomisation, blinding, follow up duration, follow up loss, depression scores and medical outcome. The database search revealed 4464 articles. The review yielded 19 trials. Antidepressant and/or psychotherapy did not significantly influence CAD outcomes in the overall population. There was no difference between antidepressant use and aerobic exercises. Psychological interventions and pharmacological interventions provide small effect on depression outcomes in CAD patients. Patient autonomy in choice of treatment is associated with greater depression treatment satisfaction, but the majority of studies are underpowered. More research is required to explore the role of neurostimulation treatment, complementary and alternative treatments.

Details

Title: Management of depression in patients with coronary artery disease: A systematic review
Authors: Wole Akosile (Corresponding Author) - The University of Queensland
Babangida Tiyatiye (Author) - The University of Western Australia
David Colquhoun (Author) - The University of Queensland
Ross Young (Author) - University of the Sunshine Coast, Queensland, Office of the Deputy Vice-Chancellor (Research and Innovation)
Publication details: Asian Journal of Psychiatry, Vol.83, pp.1-15
Publisher: Elsevier BV
Date published: 2023
DOI: 10.1016/j.ajp.2023.103534
ISSN: 1876-2026
PMID: 36871435
Organisation Unit: Office of the Deputy Vice-Chancellor (Research and Innovation); Thompson Institute
Language: English
Record Identifier: 99711298502621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Psychiatry

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