Macrotricolorin A, a new diarylpropanoid from the Vietnamese plant Macrosolen tricolor (Lecomte) Danser

Kieu Hung Le; Thi Kim Ngan Bui; Nguyen Kim Tuyen Pham; Van Son Dang; Trong Nghia Ngo; Nhat Minh Phan; Trong Dat Bui; Trong Duc Tran; Quan Hien Nguyen; Quoc Luan Ngo; Dinh Tri Mai; Tan Phat Nguyen

doi:10.1080/14786419.2020.1771710

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Macrotricolorin A, a new diarylpropanoid from the Vietnamese plant Macrosolen tricolor (Lecomte) Danser

Journal article

Peer reviewed

Macrotricolorin A, a new diarylpropanoid from the Vietnamese plant Macrosolen tricolor (Lecomte) Danser

Kieu Hung Le, Thi Kim Ngan Bui, Nguyen Kim Tuyen Pham, Van Son Dang, Trong Nghia Ngo, Nhat Minh Phan, Trong Dat Bui, Trong Duc Tran, Quan Hien Nguyen, Quoc Luan Ngo, …

Natural Product Research, Vol.36(1), pp.165-170

2022

DOI: https://doi.org/10.1080/14786419.2020.1771710

PMID: 32490695

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Abstract

Macrosolen tricolor

macrotricolorin A

Loranthaceae

diarylalkanoid

anti-inflammatory activity

From the Vietnamese plant Macrosolen tricolor (Lecomte) Danser, one new diarylpropanoid, named macrotricolorin A (1) together with three diarylheptanoids including bisdemethoxycurcumin (2), demethoxycurcumin (3) and curcumin (4), were isolated. Their structures were elucidated by intensive analyses of their IR, UV, HR-ESI-MS and NMR (1 D & 2 D) spectra. It is the first time that diarylalkanoids have been reported from the genus Macrosolen. Compound 1 exhibited anti-inflammatory activity against the nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW264.7 with an IC 50 value of 27.54 ± 1.75 μM.

Details

Title: Macrotricolorin A, a new diarylpropanoid from the Vietnamese plant Macrosolen tricolor (Lecomte) Danser
Authors: Kieu Hung Le (Author) - Vietnam Academy of Science and Technology
Thi Kim Ngan Bui (Author) - Saigon University
Nguyen Kim Tuyen Pham (Author) - Saigon University
Van Son Dang (Author) - Vietnam Academy of Science and Technology
Trong Nghia Ngo (Author) - Kien Giang University (Vietnam)
Nhat Minh Phan (Author) - Vietnam Academy of Science and Technology
Trong Dat Bui (Author) - Vietnam Academy of Science and Technology
Trong Duc Tran (Author) - University of the Sunshine Coast, Queensland, School of Science and Engineering - Legacy
Quan Hien Nguyen (Author) - Ho Chi Minh City Institute of Physics
Quoc Luan Ngo (Author) - Can Tho University
Dinh Tri Mai (Author) - Vietnam Academy of Science and Technology
Tan Phat Nguyen (Author) - Vietnam Academy of Science and Technology
Publication details: Natural Product Research, Vol.36(1), pp.165-170
Publisher: Taylor & Francis
Date published: 2022
DOI: 10.1080/14786419.2020.1771710
ISSN: 1478-6427
PMID: 32490695
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering; Centre for Bioinnovation
Language: English
Record Identifier: 99469908202621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Chemistry, Applied; Chemistry, Medicinal

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