Lymphopenia is observed regularly in the acute (leptospiraemic) phase but not the immune phase of leptospirosis

Scott B Craig; Glenn C Graham; M A Burns; M F Dohnt; Lee D Smythe; David B McKay

doi:10.1016/j.trstmh.2009.03.019

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Lymphopenia is observed regularly in the acute (leptospiraemic) phase but not the immune phase of leptospirosis

Journal article

Peer reviewed

Lymphopenia is observed regularly in the acute (leptospiraemic) phase but not the immune phase of leptospirosis

Scott B Craig, Glenn C Graham, M A Burns, M F Dohnt, Lee D Smythe and David B McKay

Royal Society of Tropical Medicine and Hygiene. Transactions, Vol.103(9), pp.958-960

2009

DOI: https://doi.org/10.1016/j.trstmh.2009.03.019

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Abstract

leptospirosis

lymphopenia

lymphocyte count

laboratory findings

emerging disease

zoonosis

Lymphocyte counts in patients with leptospirosis have been shown to be variable. This study retrospectively compared lymphocyte counts from the first blood samples taken following hospital presentation in patients with leptospirosis who were either (i) IgM non-reactive, (ii) IgM reactive and microscopic agglutination test (MAT) non-reactive or (iii) IgM and MAT reactive in an effort to determine whether differences in lymphocyte counts are observed in the acute and immune phase of leptospirosis. Statistical differences in lymphocyte counts were observed between the three groups. In conclusion, this study has shown that the phase of leptospiral infection may affect patient lymphocyte counts.

Details

Title: Lymphopenia is observed regularly in the acute (leptospiraemic) phase but not the immune phase of leptospirosis
Authors: Scott B Craig (Author) - University of the Sunshine Coast - Faculty of Science, Health and Education
Glenn C Graham (Author) - Queensland Health Forensic and Scientific Service
M A Burns (Author) - Queensland Health Forensic and Scientific Service
M F Dohnt (Author) - Queensland Health Forensic and Scientific Service
Lee D Smythe (Author) - Queensland Health Forensic and Scientific Service
David B McKay (Author) - University of the Sunshine Coast - Faculty of Science, Health and Education
Publication details: Royal Society of Tropical Medicine and Hygiene. Transactions, Vol.103(9), pp.958-960
Publisher: Elsevier Ltd.
Date published: 2009
DOI: 10.1016/j.trstmh.2009.03.019
ISSN: 0035-9203
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99449419902621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Public, Environmental & Occupational Health; Tropical Medicine

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