Localized Outbreaks of Epidemic Polyarthritis among Military Personnel Caused by Different Sublineages of Ross River Virus, Northeastern Australia, 2016-2017

Wenjun Liu; Joanne R. Kizu; Luke R. Le Grand; Christopher Moller; Tracy L. Carthew; Ian R. Mitchell; Ania J. Gubala; John G Aaskov

doi:10.3201/eid2510.181610

Back

Localized Outbreaks of Epidemic Polyarthritis among Military Personnel Caused by Different Sublineages of Ross River Virus, Northeastern Australia, 2016-2017

Journal article

Peer reviewed

Localized Outbreaks of Epidemic Polyarthritis among Military Personnel Caused by Different Sublineages of Ross River Virus, Northeastern Australia, 2016-2017

Wenjun Liu, Joanne R. Kizu, Luke R. Le Grand, Christopher Moller, Tracy L. Carthew, Ian R. Mitchell, Ania J. Gubala and John G Aaskov

Emerging Infectious Diseases, Vol.25(10), pp.1793-1801

2019

DOI: https://doi.org/10.3201/eid2510.181610

PMID: 31538560

Files and links (1)

url

https://doi.org/10.3201/eid2510.181610View

Published Version Open

Abstract

Public health

Infectious diseases

Immunology

Infectious Diseases

Life Sciences & Biomedicine

Science & Technology

Two outbreaks of epidemic polyarthritis occurred among Australian Defence Force personnel during and following short military exercises in the Shoalwater Bay Training Area, northeastern Australia, in 2016 and 2017. Ross River virus (RRV) IgM was detected in acute-phase serum samples from most patients (28/28 in 2016 and 25/31 in 2017), and RRV was recovered from 4/38 serum samples assayed (1/21 in 2016 and 3/17 in 2017). Phylogenetic analyses of RRV envelope glycoprotein E2 and nonstructural protein nsP3 nucleotide sequences segregated the RRV isolates obtained in 2016 and 2017 outbreaks into 2 distinct sublineages, suggesting that each outbreak was caused by a different strain of RRV. The spatiotemporal characteristics of the 2016 outbreak suggested that some of the infections involved human-mosquito-human transmission without any intermediate host. These outbreaks highlight the importance of personal protective measures in preventing vectorborne diseases for which no vaccine or specific prophylaxis exists.

Details

Title: Localized Outbreaks of Epidemic Polyarthritis among Military Personnel Caused by Different Sublineages of Ross River Virus, Northeastern Australia, 2016-2017
Authors: Wenjun Liu (Corresponding Author) - Australian Defence Force Malaria and Infectious Disease Institute
Joanne R. Kizu - Australian Defence Force Malaria and Infectious Disease Institute
Luke R. Le Grand - Australian Defence Force Malaria and Infectious Disease Institute
Christopher Moller - Australian Defence Force Malaria and Infectious Disease Institute
Tracy L. Carthew - Australian Defence Force Malaria and Infectious Disease Institute
Ian R. Mitchell - Defence Science and Technology Group
Ania J. Gubala - Defence Science and Technology Group
John G Aaskov - Queensland University of Technology
Publication details: Emerging Infectious Diseases, Vol.25(10), pp.1793-1801
Publisher: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention
Date published: 2019
DOI: 10.3201/eid2510.181610
ISSN: 1080-6059
PMID: 31538560
Grant note: Joint Health Command of the Australian Defence Force funded this investigation.
Organisation Unit: UniSC Clinical Trials Centre
Language: English
Record Identifier: 991253099602621
Output Type: Journal article

Metrics

1 Record Views

19 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Web Of Science research areas: Immunology; Infectious Diseases

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: SDGs from InCites