Journal article
Ligand-Free RuCl3-Catalyzed Alkylation of Methylazaarenes with Alcohols
Journal of Organic Chemistry, Vol.82(8), pp.4113-4120
2017
Abstract
RuCl3 efficiently catalyzes the alkylation of methylquinolines, methylpyridines, 2-methyl-benzooxazoles, and 2-methyl-quinoxalines with alkyl- or aryl-alcohols as alkylating agents. This synthetically useful and atom economical transformation does not require additional ligands. The mechanistic study indicated the alkylation reaction underwent a stepwise transfer hydrogenation, aldol condensation, and hydrogenation reaction pathway.
Details
- Title
- Ligand-Free RuCl3-Catalyzed Alkylation of Methylazaarenes with Alcohols
- Authors
- Feng Tong-Yu (Author) - Shanghai Institute of Organic Chemistry, ChinaLi Hong-Xi (Author) - Sanchow University, ChinaDavid James Young (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringJian-Ping Lang (Author) - Shanghai Institute of Organic Chemistry, China
- Publication details
- Journal of Organic Chemistry, Vol.82(8), pp.4113-4120
- Publisher
- American Chemical Society
- Date published
- 2017
- DOI
- 10.1021/acs.joc.6b03095
- ISSN
- 0022-3263
- Organisation Unit
- University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99451067102621
- Output Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Chemistry, Organic