Files and links (2)
Published VersionCC BY V4.0, Open Access
Journal article
Influenza Virus and Glycemic Variability in Diabetes: A Killer Combination?
Frontiers in Microbiology, Vol.8, pp.1-7
2017
Abstract
Following the 2009 H1N1 influenza virus pandemic, numerous studies identified the striking link between diabetes mellitus and influenza disease severity. Typically, influenza virus is a self-limiting infection but in individuals who have a pre-existing chronic illness, such as diabetes mellitus, severe influenza can develop. Here, we discuss the latest clinical and experimental evidence for the role of diabetes in predisposing the host to severe influenza. We explore the possible mechanisms that underlie this synergy and highlight the, as yet, unexplored role that blood glucose oscillations may play in disease development. Diabetes is one of the world’s fastest growing chronic diseases and influenza virus represents a constant and pervasive threat to human health. It is therefore imperative that we understand how diabetes increases influenza severity in order to mitigate the burden of future influenza epidemics and pandemics.
Details
- Title
- Influenza Virus and Glycemic Variability in Diabetes: A Killer Combination?
- Authors
- Katina D Hulme (Author) - The University of QueenslandLinda Gallo (Author) - The University of QueenslandKirsty R Short (Author) - The University of Queensland
- Publication details
- Frontiers in Microbiology, Vol.8, pp.1-7
- Publisher
- Frontiers Research Foundation
- Date published
- 2017
- DOI
- 10.3389/fmicb.201700861
- ISSN
- 1664-302X
- Copyright note
- © 2017 Hulme, Gallo and Short. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Organisation Unit
- School of Health - Biomedicine; University of the Sunshine Coast, Queensland; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99620506502621
- Output Type
- Journal article
Metrics
17 Record Views