Files and links (1)
Influence of a 12-Month Structured Exercise Program on the Micronutrient-Cognitive Fitness-Physical Association Profiles in Mild Cognitive Impairment97.31 kB
Published VersionCC BY-NC V4.0, Open Access
Journal article
Influence of a 12-Month Structured Exercise Program on the Micronutrient-Cognitive Fitness-Physical Association Profiles in Mild Cognitive Impairment
Journal of Alzheimer's Disease Reports, Vol.6(1), pp.711-722
2022
Abstract
Background: Preventive lifestyle strategies have shown promise to slow down or prevent age-related cognitive decline. However, evidence on the reciprocal longitudinal relationships between nutrition biomarkers and cognitive and physical performance is lacking. Studying nutritional, cognitive, and physical profiles over time may help to overcome this knowledge gap. Objective: To investigate the relationship of plasma levels of the robust nutritional- and antioxidant defense-related biomarkers carotenoids and tocopherols with both indicators of cognitive and physical performance in persons with mild cognitive impairment (MCI) participating in a structured exercise program. Methods: Data from 40 participants with MCI of the NeuroExercise study were analyzed. Participants had undergone a blood withdrawal for the analysis of plasma concentrations of six carotenoids, two tocopherols and retinol prior to and after one-year of structured exercise. All participants had undergone a broad spectrum of cognitive and physical performance tests. Results: Significant associations between lipophilic micronutrients and cognitive/physical measures were observed that were previously found to play a role in cognitive and physical frailty. In particular, lutein, zeaxanthin, and lycopene are confirmed as robust, reliable, and stable indicators of nutritional defense. Importantly, these micronutrients were associated with cognitive measures prior to the physical training program and to a more prominent extent with indicators of motoric function after the physical exercise program. Conclusion: Specific profiles of lipophilic micronutrients are associated to cognitive performance measures and, especially after a structured exercise program, to indicators of physical performance.
Details
- Title
- Influence of a 12-Month Structured Exercise Program on the Micronutrient-Cognitive Fitness-Physical Association Profiles in Mild Cognitive Impairment
- Authors
- Hannah Weigert (Author) - University Hospital CologneTim Stuckenschneider (Author) - University of the Sunshine Coast, Queensland, School of Health and Sport Sciences - LegacyLena Pickert (Author) - University Hospital CologneAndrea Rossi (Author) - Ospedale di BolzanoAnna M. Meyer (Author) - University Hospital CologneGereon Nelles (Author) - NeuroMed Campus HohenlindRalf-Joachim Schulz (Author) - St. Marien HospitalWilhelm Stahl (Author) - Heinrich Heine University DüsseldorfStefan Schneider (Author) - University of the Sunshine Coast, Queensland, School of Health and Sport Sciences - LegacyM. Cristina Polidori (Corresponding Author) - University Hospital Cologneon behalf of the NeuroExercise Study Group (Author)
- Publication details
- Journal of Alzheimer's Disease Reports, Vol.6(1), pp.711-722
- Publisher
- IOS Press
- Date published
- 2022
- DOI
- 10.3233/ADR-220039
- ISSN
- 2542-4823
- Copyright note
- © 2021 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0).
- Organisation Unit
- School of Health and Sport Sciences - Legacy
- Language
- English
- Record Identifier
- 99696658502621
- Output Type
- Journal article
Metrics
144 File views/ downloads
75 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Neurosciences
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites