Increasing functional connectivity of the anterior cingulate cortex during the course of recovery from Bell's palsy

Sheng Hu; Yuanyuan Wu; Chuanfu Li; Kyoungok Park; Guangming Lu; Abdalla Z Mohamed; Hongli Wu; Chunsheng Xu; Wei Zhang; Linying Wang; Jun Yang; Bensheng Qiu

doi:10.1097/WNR.0000000000000295

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Increasing functional connectivity of the anterior cingulate cortex during the course of recovery from Bell's palsy

Journal article

Peer reviewed

Increasing functional connectivity of the anterior cingulate cortex during the course of recovery from Bell's palsy

Sheng Hu, Yuanyuan Wu, Chuanfu Li, Kyoungok Park, Guangming Lu, Abdalla Z Mohamed, Hongli Wu, Chunsheng Xu, Wei Zhang, Linying Wang, …

NeuroReport, Vol.26(1), pp.6-12

2015

DOI: https://doi.org/10.1097/WNR.0000000000000295

PMID: 25426823

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Abstract

Bell's palsy (BP), a unilateral and idiopathic palsy of the facial nerve, is a common disorder generally followed by a good natural recovery. The aim of this study was to investigate the relationship between the functional connectivity of the anterior cingulate cortex (ACC) and the recovery process of BP. Thirty-seven healthy volunteers and 67 patients were studied by functional MRI (fMRI). The seed regions of bilateral ACC were first extracted from the task-state fMRI data of healthy participants performing the task of mouth opening and closing. The connectivity of bilateral ACC was calculated from resting-state fMRI data of patients in whom only resting-state fMRI data were collected. The correlation between the strength of ACC's connectivity with the duration (time course of disease) was computed by analysis of covariance. It was found that the functional connectivity of the ACC ipsilateral to the lesioned side was enforced as the duration increased. The enforced brain areas included the sensorimotor areas and the ACC contralateral to the palsy. It was suggested that enforced functional connectivity of ACC might be related to cortical reorganization, which is important in the process of BP recovery.

Details

Title: Increasing functional connectivity of the anterior cingulate cortex during the course of recovery from Bell's palsy
Authors: Sheng Hu (Author) - University of Science and Technology of China
Yuanyuan Wu (Author) - Anhui University of Traditional Chinese Medicine
Chuanfu Li (Author) - Anhui University of Traditional Chinese Medicine
Kyoungok Park (Author) - Kyung Hee University
Guangming Lu (Author) - Chinese PLA General Hospital
Abdalla Z Mohamed (Author) - Kyung Hee University
Hongli Wu (Author) - Anhui University of Traditional Chinese Medicine
Chunsheng Xu (Author) - Anhui University of Traditional Chinese Medicine
Wei Zhang (Author) - Anhui University of Traditional Chinese Medicine
Linying Wang (Author) - Anhui University of Traditional Chinese Medicine
Jun Yang (Author) - Anhui University of Traditional Chinese Medicine
Bensheng Qiu (Author) - University of Science and Technology of China
Publication details: NeuroReport, Vol.26(1), pp.6-12
Publisher: Lippincott Williams & Wilkins
DOI: 10.1097/WNR.0000000000000295
ISSN: 1473-558X
PMID: 25426823
Organisation Unit: Thompson Institute; University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99522405202621
Output Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Neurosciences

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