Journal article
Incidence of type 1 diabetes in children in Dominican Republic, 2010-2019: A national collaborative study
Pediatric Diabetes, Vol.23(7), pp.976-981
2022
PMID: 35689539
Abstract
Background:
The Dominican Republic has no recent data on type 1 diabetes (T1D) incidence in children. Therefore, a study was undertaken to determine this in persons aged <15 years (y).
Methods:
Data were collected on all new T1D diagnoses between 2010-2019 from the four institutions caring for children with T1D. Diagnosis was made according to standard criteria. No secondary ascertainment source was available. The trend and the effect of age and sex of T1D incidence was analysed using Poisson regression.
Results:
1,224 new cases of T1D were diagnosed <15 y; mean±standard deviation (range) 122±12 (96-135) cases per year. Age at T1D diagnosis was 8.8±3.7 y, with a significant female preponderance (n=708, 57.8%, p<0.001). When examined per 5-y age group, cases were consistently highest in 10-14 y, and lowest in 0-4 y in all study years.
Mean crude T1D annual incidence was 4.3 (95% CI 3.5-5.1) per 100,000 population. There was no significant difference between incidence across the country's three departments (regions): Southeast (4.4 (3.4-5.7)/100,000 population), North (4.1 (2.9-5.6)) and Southwest (3.9 (2.4-5.9)). Mean standardised annual incidence was 4.1 (4.1-4.2) per 100,000 population, with no significant trend of increase over the study period.
Conclusions:
The incidence of diabetes in children aged <15 y is relatively low in Dominican Republic, but consistent with the limited data from other countries in the region. However, the incidence is eight times higher than the previous estimate during 1995-1999. Ongoing surveillance is warranted.
Details
- Title
- Incidence of type 1 diabetes in children in Dominican Republic, 2010-2019: A national collaborative study
- Authors
- Elbi Morla (Corresponding Author)Ammar Ibrahim (Author)Graham D Ogle (Author) - Diabetes NSWSteven James (Author) - University of the Sunshine Coast, Queensland, School of Nursing, Midwifery and Paramedicine - LegacyJayanthi Maniam (Author) - Diabetes NSWRosario Almanzar (Author)Carmen Rosario (Author)Angela Matos (Author)Lourdes Ruiz (Author)Patricia Martinez (Author)Jose Lopez (Author)
- Publication details
- Pediatric Diabetes, Vol.23(7), pp.976-981
- Publisher
- Wiley-Blackwell Publishing, Inc.
- Date published
- 2022
- DOI
- 10.1111/pedi.13380
- ISSN
- 1399-5448
- PMID
- 35689539
- Copyright note
- This is the peer reviewed version of the following article: Morla, E., Ibrahim, A., Ogle, G.D., James, S., Maniam, J., Almanzar, R., Rosario, C., Matos, A., Ruiz, L., Martinez, P. and Lopez, J. (2022), Incidence of type 1 diabetes in children in Dominican Republic, 2010-2019: A national collaborative study. Pediatr Diabetes. Accepted Author Manuscript. https://doi.org/10.1111/pedi.13380, which has been published in final form at https://doi.org/10.1111/pedi.13380. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
- Grant note
- The Leona M and Harry B Helmsley Charitable Trust (GDO and JM).
- Organisation Unit
- School of Health - Nursing; School of Nursing, Midwifery and Paramedicine - Legacy; University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99649778702621
- Output Type
- Journal article
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- International collaboration
- Web Of Science research areas
- Endocrinology & Metabolism
- Pediatrics
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