Improved biodegradable magnesium alloys through advanced solidification processing

M S Dargusch; N Balasubramani; J Venezuela; S Johnston; G Wang; C Lau; M Bermingham; Damon Kent; D H StJohn

doi:10.1016/j.scriptamat.2019.10.028

Back

Improved biodegradable magnesium alloys through advanced solidification processing

Journal article

Peer reviewed

Improved biodegradable magnesium alloys through advanced solidification processing

M S Dargusch, N Balasubramani, J Venezuela, S Johnston, G Wang, C Lau, M Bermingham, Damon Kent and D H StJohn

Scripta Materialia, Vol.177, pp.234-240

2020

DOI: https://doi.org/10.1016/j.scriptamat.2019.10.028

Files and links (1)

url

https://doi.org/10.1016/j.scriptamat.2019.10.028View

Published Version

Abstract

grain refinement

ultrasonic treatment

Mg-Zn-Ca alloy

biodegradation

The potential of using external fields to reduce the cost of emerging magnesium alloys used for the manufacture of medical implant devices while maintaining biocompatibility and mechanical performance is explored. Zirconium (Zr) is often added to high performance magnesium alloys as a grain refiner which is expensive, and there is uncertainty about whether or not Zr is harmful to the biocompatibility of the alloy. This is a significant barrier to the adoption of alloys that contain Zr because of the need to undertake cytotoxicity and haemocompatibility testing, as well as evaluation of long-term clinical effects. An alternative approach is to investigate methods to minimise or eliminate the need for Zr addition. External fields applied during solidification of the alloy provide an opportunity to produce a refined microstructure without the addition of Mg-Zr master alloy presenting a distinct advantage both from biodegradation and biocompatibility perspectives. Preliminary work evaluates the effect of ultrasonic treatment on microstructure and mechanical properties of Mg-Zn-Ca alloys with and without Zr and then compares their in-vivo corrosion performance to that of WE43. A framework for future research is proposed along with opportunities for the development of lower cost alloys with at least equal biocompatibility, mechanical and corrosion performance.

Details

Title: Improved biodegradable magnesium alloys through advanced solidification processing
Authors: M S Dargusch (Author) - University of Queensland
N Balasubramani (Author) - University of Queensland
J Venezuela (Author) - University of Queensland
S Johnston (Author) - University of Queensland
G Wang (Author) - University of Queensland
C Lau (Author) - University of Queensland
M Bermingham (Author) - University of Queensland
Damon Kent (Author) - University of the Sunshine Coast - School of Science & Engineering
D H StJohn (Author) - University of Queensland
Publication details: Scripta Materialia, Vol.177, pp.234-240
Publisher: Elsevier Ltd.
Date published: 2020
DOI: 10.1016/j.scriptamat.2019.10.028
ISSN: 1359-6462
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99451366502621
Output Type: Journal article

Metrics

348 Record Views

28 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Web Of Science research areas: Materials Science, Multidisciplinary; Metallurgy & Metallurgical Engineering; Nanoscience & Nanotechnology