Impact of Physical Activity and BMI on Health-Related Quality of Life in Overweight Indian Adolescents: A Randomized Controlled Study

Prateek Srivastav; Vaishali K; H Vinod Bhat; Suzanne Broadbent

doi:10.1016/j.obpill.2025.100201

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Impact of Physical Activity and BMI on Health-Related Quality of Life in Overweight Indian Adolescents: A Randomized Controlled Study

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Impact of Physical Activity and BMI on Health-Related Quality of Life in Overweight Indian Adolescents: A Randomized Controlled Study

Prateek Srivastav, Vaishali K, H Vinod Bhat and Suzanne Broadbent

Obesity Pillars, Vol.16, pp.1-7

2025

DOI: https://doi.org/10.1016/j.obpill.2025.100201

PMCID: PMC12397862

PMID: 40894181

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Abstract

health-related quality of life

adolescents

obesity

physical activity

BMI

India

randomized controlled trial

Background Health-related quality of life (HRQOL) is a critical yet often overlooked component of adolescent obesity management. While physical activity (PA) and body mass index (BMI) are established markers of health, their combined influence on HRQOL in Indian adolescents remains underexplored. Objective To examine how PA and BMI influence overall and domain-specific HRQOL in overweight and adolescents with obesity following a structured lifestyle program. Methods In this randomized controlled study, 604 adolescents (aged 11–16 years) with BMI above the 85th percentile were recruited from schools in Udupi, India. Individuals were randomized into three groups: multifactorial strategy (MFI: exercise, lifestyle education, behavioral counseling), exercise-only (EX), and Control group (CON). PA was measured using the Physical Activity Questionnaire for Adolescents (PAQ-A), and HRQOL was measured via the Pediatric Quality of Life Inventory (PedsQL 4.0). Linear mixed-effects models evaluated associations between PA, BMI, and HRQOL over a 12-month period, which included a 12-week intervention followed by 9 months of follow-up. Results PA was linked with better HRQOL in the MFI (β = 9.30, p < 0.001) and EX (β = 4.47, p < 0.001) groups. Interestingly, higher BMI correlated with better HRQOL scores in both program arms. The CON group showed no meaningful association between PA and HRQOL. The domain-level analysis found that PA and BMI were positively linked to physical, emotional, social, and school functioning in both program groups, with more pronounced effects in the MFI group. The CON group showed improvement only in emotional functioning related to BMI. Conclusion Structured PA programs, especially those combining education and behavioral support, notably enhance the quality of life among overweight Indian adolescents. These findings reinforce the importance of focusing not solely on weight loss, but on holistic, behavior-driven health outcomes in adolescent obesity care. Clinical Trial Registration CTRI/2019/04/018834

Details

Title: Impact of Physical Activity and BMI on Health-Related Quality of Life in Overweight Indian Adolescents: A Randomized Controlled Study
Authors: Prateek Srivastav - Manipal Academy of Higher Education
Vaishali K (Corresponding Author) - Manipal Academy of Higher Education
H Vinod Bhat - Apollo University (India)
Suzanne Broadbent - University of the Sunshine Coast, Queensland, School of Health - Sports & Exercise Science
Publication details: Obesity Pillars, Vol.16, pp.1-7
Publisher: Elsevier Inc.
Date published: 2025
DOI: 10.1016/j.obpill.2025.100201
ISSN: 2667-3681
PMID: 40894181; PMC12397862
Organisation Unit: Healthy Ageing Research Cluster; Cancer Research Cluster; Engage Research Lab; School of Health - Sports & Exercise Science
Language: English
Record Identifier: 991154338802621
Output Type: Journal article

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