Journal article
Immunocytochemical localization of thioredoxin in human trophoblast and decidua
Placenta , Vol.16(7), pp.635-642
1995
PMID: 8577662
Abstract
An immunocytochemical investigation into the expression of thioredoxin in human reproductive tissues was performed using monoclonal antibodies produced against recombinant human thioredoxin. First trimester and term human placental villi, decidua and term fetal membranes were examined for thioredoxin content and cellular localization. In first trimester tissue strong thioredoxin staining was observed in the underlying cytotrophoblast cells and in the stromal cells present in the decidua, but not in the syncytiotrophoblast surrounding the chorionic villi. In term placental villi very little thioredoxin was observed. Term fetal membranes proved to be a rich source of thioredoxin, the most intense staining was seen in the cytotrophoblast cells in the chorionic membrane, with the amnion and decidua also showing positive immunoreactivity. The potential role/s that thioredoxin may play within the placental bed is considered.
Details
- Title
- Immunocytochemical localization of thioredoxin in human trophoblast and decidua
- Authors
- A. V Perkins (Author) - John Radcliffe HospitalG Di Trapani (Author) - Griffith UniversityM. S Mckay (Author) - Griffith UniversityF. M Clarke (Corresponding Author) - Griffith University
- Publication details
- Placenta , Vol.16(7), pp.635-642
- Publisher
- Elsevier Ltd.
- DOI
- 10.1016/0143-4004(95)90032-2
- ISSN
- 1532-3102
- PMID
- 8577662
- Organisation Unit
- School of Health and Behavioural Sciences - Legacy; School of Health
- Language
- English
- Record Identifier
- 99685197402621
- Output Type
- Journal article
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- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Developmental Biology
- Obstetrics & Gynecology
- Reproductive Biology
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