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Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae
Journal article   Peer reviewed

Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae

H Shams-Eldin, Bonnie L Chaban, S Niehus, R T Schwarz and K F Jarrell
Journal of Bacteriology, Vol.190(6), pp.2217-2220
2008
url
https://doi.org/10.1128/JB.01778-07View
Published Version

Abstract

The Mv1751 gene product is thought to catalyze the first step in the N-glycosylation pathway in Methanococcus voltae. Here, we show that a conditional lethal mutation in the alg7 gene (N-acetylglucosamine-1-phosphate transferase) in Saccharomyces cerevisiae was successfully complemented with Mv1751, highlighting a rare case of cross-domain complementation. Copyright © 2008, American Society for Microbiology. All Rights Reserved.

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