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Identification of bioactives from the red seaweed Asparagopsis taxiformis that promote antimethanogenic activity in vitro
Journal article   Peer reviewed

Identification of bioactives from the red seaweed Asparagopsis taxiformis that promote antimethanogenic activity in vitro

L Machado, M Magnusson, Nicholas A Paul, R Kinley, R de Nys and N Tomkins
Journal of Applied Phycology, Vol.28(5), pp.3117-3126
2016
url
https://doi.org/10.1007/s10811-016-0830-7View
Published Version

Abstract

bromoform methane inhibitors natural products red macroalgae rhodophyta seaweed
Asparagopsis taxiformis has potent antimethanogenic activity as a feed supplement at 2 % of organic matter in in vitro bioassays. This study identified the main bioactive natural products and their effects on fermentation using rumen fluid from Bos indicus steers. Polar through to non-polar extracts (water, methanol, dichloromethane and hexane) were tested. The dichloromethane extract was most active, reducing methane production by 79 %. Bromoform was the most abundant natural product in the biomass of Asparagopsis (1723 μg g-1 dry weight [DW] biomass), followed by dibromochloromethane (15.8 μg g-1 DW), bromochloroacetic acid (9.8 μg g-1 DW) and dibromoacetic acid (0.9 μg g-1 DW). Bromoform and dibromochloromethane had the highest activity with concentrations ≥1 μM inhibiting methane production. However, only bromoform was present in sufficient quantities in the biomass at 2 % organic matter to elicit this effect. Importantly, the degradability of organic matter and volatile fatty acids were not affected at effective concentrations. © 2016, Springer Science+Business Media Dordrecht.

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Biotechnology & Applied Microbiology
Marine & Freshwater Biology

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