HtrA, RseP, and Tsp proteins do not elicit a pathology-related serum IgG response during sexually transmitted infection with Chlamydia trachomatis

W M Huston; C W Armitage; A Lawrence; S Gloeckl; S J Bell; J Debattista; John A Allan; Peter Timms

doi:10.1016/j.jri.2010.02.007

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HtrA, RseP, and Tsp proteins do not elicit a pathology-related serum IgG response during sexually transmitted infection with Chlamydia trachomatis

Journal article

Open access

Peer reviewed

HtrA, RseP, and Tsp proteins do not elicit a pathology-related serum IgG response during sexually transmitted infection with Chlamydia trachomatis

W M Huston, C W Armitage, A Lawrence, S Gloeckl, S J Bell, J Debattista, John A Allan and Peter Timms

Journal of Reproductive Immunology, Vol.85(2), pp.168-171

2010

DOI: https://doi.org/10.1016/j.jri.2010.02.007

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Abstract

Chlamydia

Serum IgG

infertility

Tsp

HtrA

Chlamydia trachomatis sexually transmitted infection can cause serious reproductive morbidities. This study determined the prevalence of a serum IgG response to C. trachomatis putative stress response proteins in women, to test for an association with genital tract pathology. There was no significant association of serum IgG reactive with C. trachomatis HtrA, Tsp, or RseP with infection or pathology. cHSP60 serum IgG prevalence was significantly associated with infection compared to IgG negative infertile controls, but not with upper genital tract pathology. Serum IgG1-4 antibody subclasses reactive with these antigens was not significantly different between cohorts, although different responses to each antigen were detected. © 2010.

Details

Title: HtrA, RseP, and Tsp proteins do not elicit a pathology-related serum IgG response during sexually transmitted infection with Chlamydia trachomatis
Authors: W M Huston (Author) - Queensland University of Technology
C W Armitage (Author) - Queensland University of Technology
A Lawrence (Author) - Queensland University of Technology
S Gloeckl (Author) - Queensland University of Technology
S J Bell (Author) - Queensland University of Technology
J Debattista (Author) - Queensland University of Technology
John A Allan (Author) - Queensland University of Technology
Peter Timms (Author) - Queensland University of Technology
Publication details: Journal of Reproductive Immunology, Vol.85(2), pp.168-171
Publisher: Elsevier Ireland Ltd.
Date published: 2010
DOI: 10.1016/j.jri.2010.02.007
ISSN: 0165-0378
Organisation Unit: University of the Sunshine Coast, Queensland; Centre for Bioinnovation
Language: English
Record Identifier: 99449810502621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Immunology; Obstetrics & Gynecology; Reproductive Biology

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