Journal article
Home Polysomnography in Children With Autism Spectrum Disorder: A Prospective Observational Study
Journal of Sleep Research, Vol.Advanced access, e70265
2025
Abstract
This prospective observational study reports on the feasibility and adequacy of Level 2 polysomnography involving children with autism spectrum disorder during an interventional-randomised controlled trial. Multiple level 2 polysomnographic studies were performed using Nox-A1 devices worn between October 2023 and September 2024. Study feasibility was determined by the child's compliance and primary caregiver report, while signal quality (key channels present for at least 90% of sleep time) was used to define study adequacy. A cost analysis was also conducted. Twenty children (6–12 years, 9.1 + 1.55 years; 16 males) with autism spectrum disorder (level 2) and reported sleep difficulties participated in the study. Eighty (89%) of 90 polysomnographic studies were feasible. All infeasible studies, except one, were unrelated to the study. Seventy-four (93%) of the eighty studies resulted in adequate study quality. Most (n = 6, 7%) inadequate studies were due to electroencephalogram signal artefact/absence. The participants did not have a sleep disorder requiring medical attention. The cost of a study was estimated at $AUD 258. The study indicates the feasibility, adequacy, and cost-effectiveness of level 2 polysomnography in evaluating sleep outcomes in children with autism spectrum disorder during an interventional randomised controlled trial. This preliminary study provides valuable insights into the field of paediatric sleep medicine. Repeat studies of this method using diverse and larger sample sizes are warranted.
Details
- Title
- Home Polysomnography in Children With Autism Spectrum Disorder: A Prospective Observational Study
- Authors
- Uchenna Ezedinma (Corresponding Author) - University of the Sunshine Coast, Queensland, Thompson InstituteScott Burgess - QCLSS-AUJanet Greenhill - QCLSS-AUJyoti Singh - Brain Treatment Centre AustraliaEvan JonesAndrew Ladhams - The University of QueenslandGary Campbell - University of the Sunshine Coast, Queensland, School of HealthShauna Fjaagesund - University of the Sunshine Coast, Queensland, Thompson InstitutePiotr Swierkowski - University of the Sunshine Coast, Queensland, School of Business and Creative IndustriesAlexandra Metse - University of the Sunshine Coast, Queensland, School of Health - PsychologyTerri Downer - University of the Sunshine Coast, Queensland, School of Health - MidwiferyFlorin Oprescu - University of the Sunshine Coast
- Publication details
- Journal of Sleep Research, Vol.Advanced access, e70265
- Publisher
- Wiley-Blackwell Publishing Ltd.
- DOI
- 10.1111/jsr.70265
- ISSN
- 1365-2869
- Data Availability
- The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
- Grants
- Evaluating an alternative therapy to sleep disorders in children with autism spectrum disorder, 0980027787, University of the Sunshine Coast (Australia, Sunshine Coast) - UniSC
- Grant note
- The study received funding from TMS IP Pty, Queensland's Children Sleep Specialist Clinic, Australia.
- Organisation Unit
- School of Business and Creative Industries; Healthy Ageing Research Cluster; Centre for International Development, Social Entrepreneurship and Leadership; School of Health; Thompson Institute; Engage Research Lab; School of Health - Psychology; School of Health - Midwifery; School of Health - Public Health
- Language
- English
- Record Identifier
- 991190945902621
- Output Type
- Journal article
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