High-sensitivity cardiac troponins: no more 'negatives'

J H Gamble; E W Carlton; W P Orr; Kim Greaves

doi:10.1586/14779072.2013.828978

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High-sensitivity cardiac troponins: no more 'negatives'

Journal article

Peer reviewed

High-sensitivity cardiac troponins: no more 'negatives'

J H Gamble, E W Carlton, W P Orr and Kim Greaves

Expert review of cardiovascular therapy, Vol.11(9), pp.1129-1139

2013

DOI: https://doi.org/10.1586/14779072.2013.828978

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Abstract

acute myocardial infarction

cardiac diagnostic techniques

cardiovascular

chest pain

high-sensitivity cardiac troponins

troponin assays troponin

According to recently published expert guidelines, cardiac troponins are the only accepted biomarkers to define acute myocardial infarction. New high sensitivity cardiac troponin assays provide exciting opportunities for early rule-out and rule-in strategies and for identifying high-risk patients early in their presentation to guide early treatment and intervention. This review briefly discusses the history of troponin testing, before going on to cover clinical uses of the new highly sensitive assays in the early assessment of acute myocardial infection. Common clinical pitfalls with the use of these assays are discussed, as is the use of highly sensitive troponins more widely as prognostic markers. Likely future developments in this area are discussed.

Details

Title: High-sensitivity cardiac troponins: no more 'negatives'
Authors: J H Gamble (Author) - John Radcliffe Hospital, United Kingdom
E W Carlton (Author) - Poole Hospital NHS Foundation Trust, United Kingdom
W P Orr (Author) - Royal Berkshire NHS Foundation Trust, United Kingdom
Kim Greaves (Author) - John Radcliffe Hospital, United Kingdom
Publication details: Expert review of cardiovascular therapy, Vol.11(9), pp.1129-1139
Publisher: Taylor & Francis Ltd.
Date published: 2013
DOI: 10.1586/14779072.2013.828978
ISSN: 1744-8344
Organisation Unit: Faculty of Science, Health, Education and Engineering; University of the Sunshine Coast, Queensland
Language: English
Record Identifier: 99449495902621
Output Type: Journal article

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Collaboration types: Domestic collaboration
Web Of Science research areas: Cardiac & Cardiovascular Systems

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