Journal article
High incidence of type 1 diabetes in adolescents and young adults in Eritrea
Diabetic Medicine, Vol.38(7), pp.1-7
2021
PMID: 33587788
Abstract
Background: Eritrea has no data on type 1 diabetes incidence in children and youth, therefore a study was undertaken to determine this in persons aged <25 years (y). Methods: Data were collected on new type 1 diabetes diagnoses during 2019, from district, provincial and national hospitals. Type 1 diabetes was diagnosed according to standard WHO criteria. No secondary ascertainment source was available. 95% confidence intervals were computed based on approximation to the Poisson distribution, and age and gender effects were analysed with Poisson regression. Results: There were 532 new cases of type 1 diabetes. Mean±SD (minimum‐maximum) age of diagnosis was 16.2±5.7 (1.5‐24.9) y, and peak age group was 15‐19 y (n=200, 37.6%), with mode at 18 y. Incidence <15 y was 11.5/100,000 individuals [9.9‐13.2], with the highest incidence in the 10‐14 y group (19.0/100,000 [15.5‐23.1]). Incidence then peaked in the 15‐19 y age group (50.2/100,000 [43.5‐57.7]) and remained high in the 20‐24 y group (46.2/100,000 [39.0‐54.3]). There was a male:female ratio of 1.37 (p=0.001). Two hundred and thirty‐eight (44.7%) presented in diabetic ketoacidosis. Conclusion: Type 1 diabetes incidence in Eritrea is moderate <15 y, and high 15‐24 y. The 15‐19 and 20‐24 y rates appear to be the highest published to date. Given the study was only for one year, further confirmatory prospective information will clarify the situation and document trends. Assessment of the type 1 diabetes phenotypes that are occurring in Eritrea is also indicated.
Details
- Title
- High incidence of type 1 diabetes in adolescents and young adults in Eritrea
- Authors
- Goitom Mebrahtu (Author) - Eritrean National Diabetic Association, Asmara, EritreaJayanthi Maniam (Author) - Life for a Child Program, Diabetes NSW & ACT, Sydney, AustraliaSteven James (Author) - University of the Sunshine Coast, Queensland, School of Nursing, Midwifery and Paramedicine - LegacyGraham D Ogle (Corresponding Author) - Life for a Child Program, Diabetes NSW & ACT, Sydney, Australia
- Publication details
- Diabetic Medicine, Vol.38(7), pp.1-7
- Publisher
- Wiley-Blackwell Publishing Ltd.
- Date published
- 2021
- DOI
- 10.1111/dme.14544
- ISSN
- 1464-5491
- PMID
- 33587788
- Copyright note
- This is the peer reviewed version of the following article: Mebrahtu, G., Maniam, J., James, S. and Ogle, G.D. (2021), High incidence of type 1 diabetes in adolescents and young adults in Eritrea. Diabet Med, 38: e14544. https://doi.org/10.1111/dme.14544, which has been published in final form at https://doi.org/10.1111/dme.14544. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited
- Organisation Unit
- School of Health; School of Health - Nursing; University of the Sunshine Coast, Queensland; School of Nursing, Midwifery and Paramedicine - Legacy
- Language
- English
- Record Identifier
- 99511307402621
- Output Type
- Journal article
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