Journal article
High Quality Bioreplication of Intricate Nanostructures from a Fragile Gecko Skin Surface with Bactericidal Properties
Scientific Reports, Vol.7(41023)
2017
Abstract
The external epithelial surfaces of plants and animals are frequently carpeted with small micro- and nanostructures, which broadens their adaptive capabilities in challenging physical habitats. Hairs and other shaped protuberances manage with excessive water, light contaminants, predators or parasites in innovative ways. We are interested in transferring these intricate architectures onto biomedical devices and daily-life surfaces. Such a project requires a very rapid and accurate small-scale fabrication process not involving lithography. In this study, we describe a simple benchtop biotemplating method using shed gecko lizard skin that generates duplicates that closely replicate the small nanotipped hairs (spinules) that cover the original skin. Synthetic replication of the spinule arrays in popular biomaterials closely matched the natural spinules in length. More significantly, the shape, curvature and nanotips of the synthetic arrays are virtually identical to the natural ones. Despite some small differences, the synthetic gecko skin surface resisted wetting and bacterial contamination at the same level as natural shed skin templates. Such synthetic gecko skin surfaces are excellent platforms to test for bacterial control in clinical settings. We envision testing the biocidal properties of the well-matched templates for fungal spores and viral resistance in biomedicine as well as co/multi-cultures.
Details
- Title
- High Quality Bioreplication of Intricate Nanostructures from a Fragile Gecko Skin Surface with Bactericidal Properties
- Authors
- David William Green (Author) - Yonsei University College of Dentistry, KoreaKenneth Ka-Ho Lee (Author) - Chinese University of Hong Kong, Hong KongJolanta A Watson (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringHyun-Yi Kim (Author) - Yonsei University College of Dentistry, KoreaKyung-Sik Yoon (Author) - Yonsei University College of Dentistry, KoreaEun-Jung Kim (Author) - Yonsei University College of Dentistry, KoreaJong-Min Lee (Author) - Yonsei University College of Dentistry, KoreaGregory S Watson (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringHan-Sung Jung (Author) - Yonsei University College of Dentistry, Korea
- Publication details
- Scientific Reports, Vol.7(41023); 12
- Publisher
- Nature Publishing Group
- Date published
- 2017
- DOI
- 10.1038/srep41023
- ISSN
- 2045-2322
- Copyright note
- Copyright ©. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
- Organisation Unit
- School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
- Language
- English
- Record Identifier
- 99450910002621
- Output Type
- Journal article
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- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Materials Science, Multidisciplinary
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