Journal article
Hepatitis E virus: do locally acquired infections in Australia necessitate laboratory testing in acute hepatitis patients with no overseas travel history?
Pathology, Vol.47(2), pp.97-100
2015
PMCID: PMC4341517
PMID: 25560836
Abstract
Hepatitis E virus (HEV) is emerging as a global public health threat. Water-borne HEV outbreaks are common in developing countries and are associated with genotypes 1 and 2. In industrialised countries, sporadic cases of zoonotic transmission associated with genotypes 3 and 4 are increasingly being reported. Transfusion- and transplantation-transmitted HEV have been documented, although ingestion of contaminated food is thought to be the major transmission route. Severe disease is possible and chronic hepatitis infection occurs in solid-organ-transplant recipients andin patients with immunosuppressive disorders. In Australia, HEV cases are mainly travellers returning from disease endemic countries. Indeed, there are few reported cases of locally acquired HEV. Pigs in Australia have been shown to be infected with HEV, which indicates the possibility of zoonotic transmission. The extent of locally acquired infection is not known, however it may be greater than expected and may necessitate laboratory testing in patients reporting no overseas travel.
Details
- Title
- Hepatitis E virus: do locally acquired infections in Australia necessitate laboratory testing in acute hepatitis patients with no overseas travel history?
- Authors
- A C Shrestha (Author) - Australian Red Cross Blood ServiceHelen Faddy (Author) - University of QueenslandRobert Flower (Author) - Australian Red Cross Blood ServiceClive Seed (Author) - Australian Red Cross Blood ServiceAnthony Keller (Author) - Australian Red Cross Blood Service
- Publication details
- Pathology, Vol.47(2), pp.97-100
- Publisher
- Elsevier B.V
- DOI
- 10.1097/PAT.0000000000000229
- ISSN
- 1465-3931
- PMID
- 25560836; PMC4341517
- Organisation Unit
- School of Health and Behavioural Sciences - Legacy; School of Health and Sport Sciences - Legacy; School of Health - Biomedicine
- Language
- English
- Record Identifier
- 99477804602621
- Output Type
- Journal article
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