Journal article
Hemodynamic and Neuroendocrinological Responses to Artificial Gravity
Gravitational and Space Biology, Vol.5(2), pp.80-88
2017
Abstract
The aim of this study was to determine the hemodynamic and neuroendocrinological responses to different levels and protocols of artificial gravity, especially in comparison to what is expected during a moderate bout of exercise. Ten male participants were exposed to artificial gravity using two different protocols: the first was a centrifugation protocol that consisted of a constant phase of 2 Gz for 30 minutes, and the second consisted of an intermittent phase of 2 Gz for two minutes, separated by resting periods for three minutes in successive order. Near infrared spectroscopy (oxyhemoglobin and deoxyhemoglobin) at the prefrontal cortex, Musculus biceps brachii, and Musculus gastrocnemius, as well as heart rate and blood pressure were recorded before, during, and after exposure to artificial gravity. In order to determine effects of artificial gravity on neuroendocrinological parameters (brain-derived neurotrophic factor, vascular endothelial growth factor, and insulin-like growth factor 1), blood samples were taken before and after centrifugation. During the application of artificial gravity the concentration of oxyhemoglobin decreased significantly and the concentration of deoxyhemoglobin increased significantly in the prefrontal cortex and the Musculus biceps brachii muscle. Participants exposed to the continuous artificial gravity profile experienced peripheral pooling of blood. No changes were observed for brain-derived neurotrophic factor, vascular endothelial growth factor, or insulin-like growth factor 1. Intermittent application of artificial gravity may represent a better-tolerated presentation for participants as hemodynamic values normalize during resting periods. During both protocols, heart rate and arterial blood pressure remained far below what is experienced during moderate physical activity.
Details
- Title
- Hemodynamic and Neuroendocrinological Responses to Artificial Gravity
- Authors
- Stefan Schneider (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringVanja Sebastian Zander (Author) - German Sport University Cologne, GermanyTobias Vogt (Author) - German Sport University Cologne, GermanyVera Abeln (Author) - German Sport University Cologne, GermanyHeiko K Struder (Author) - German Sport University Cologne, GermanyAmrei Jacubowski (Author) - German Sport University Cologne, GermanyHeather Carnahan (Author) - Memorial University of Newfoundland, CanadaPetra Wollseiffen (Author) - German Sport University Cologne, Germany
- Publication details
- Gravitational and Space Biology, Vol.5(2), pp.80-88
- Publisher
- American Society of Gravitational and Space Research
- DOI
- 10.2478/gsr-2017-0012
- ISSN
- 2332-7774
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy
- Language
- English
- Record Identifier
- 99451137602621
- Output Type
- Journal article
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