adolescent cancer child healthcare costs neoplasms oncology young adult UniSC Diversity Area - Life Stages
Objective:
To collate and critically review international evidence on the direct health system costs of children and adolescents and young adults (AYA) with cancer.
Methods:
We conducted searches in PubMed, MEDLINE, CINAHL, and Scopus. Articles were limited to studies involving people aged 0–39 years at cancer diagnosis and published from 2012 to 2022. Two reviewers screened the articles and evaluated the studies using the Consolidated Health Economic Evaluation Reporting Standards checklist. The reviewers synthesized the findings using a narrative approach and presented the costs in 2022 US dollars for comparability.
Results:
Overall, the mean healthcare costs for all cancers in the 5 years post diagnosis ranged from US$36,670 among children in Korea to US$127,946 among AYA in the USA.
During the first year, the mean costs among children 0–14 years ranged from US$34,953 in Chile to over US$130,000 in Canada. These were higher than the costs for AYA, estimated at US$61,855 in Canada. At the end of life, the mean costs were estimated at over US$300,000 among children and US$235,265 among adolescents in Canada.
Leukemia was the most expensive cancer type, estimated at US$50,133 in Chile, to US$152,533 among children in Canada. Overall, more than a third of the total cost is related to hospitalizations. All the included studies were of good quality.
Conclusions:
Healthcare costs associated with cancer are substantial among children, and AYA. More research is needed on the cost of cancer in low- and middle-income countries and harmonization of costs across countries.
Details
Title
Healthcare costs of cancer among children, adolescents, and young adults: A scoping review
Authors
Doreen Nabukalu (Corresponding Author) - University of the Sunshine Coast, Queensland, School of Nursing, Midwifery and Paramedicine - Legacy
Louisa G. Gordon (Author) - QIMR Berghofer Medical Research Institute
John Lowe (Author) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - Legacy
Katharina M D Merollini (Author) - University of the Sunshine Coast, Queensland, School of Health - Public Health
The data that supports the findings of this study are available from the corresponding author upon reasonable request.
Organisation Unit
Cancer Research Cluster; School of Nursing, Midwifery and Paramedicine - Legacy; School of Health and Behavioural Sciences - Legacy; School of Health - Public Health