Journal article
Harnessing the Properties of Natural Products
Annual Review of Pharmacology and Toxicology, Vol.58, pp.451-470
2018
PMID: 28968192
Abstract
Natural products (NPs) have been used as traditional medicines since antiquity. With more than 1060 estimated compounds with molecular weights less than 500 Da representing chemical space, NPs occupy a very small percentage; however, they are significantly overrepresented in biologically relevant chemical space. The classical approach concentrates on identifying one or more NPs with biological activity from a source organism. There is much more to be learned from NPs than we can discover this narrow view. In this review, we discuss ways to harness the global properties of NPs.
Details
- Title
- Harnessing the Properties of Natural Products
- Authors
- Asmaa Boufridi (Author) - Griffith UniversityRonald J Quinn (Author) - Griffith University
- Publication details
- Annual Review of Pharmacology and Toxicology, Vol.58, pp.451-470
- Publisher
- Annual Reviews
- DOI
- 10.1146/annurev-pharmtox-010716-105029
- ISSN
- 1545-4304
- PMID
- 28968192
- Organisation Unit
- University of the Sunshine Coast, Queensland; Centre for Bioinnovation; School of Science, Technology and Engineering; School of Health - Biomedicine
- Language
- English
- Record Identifier
- 99650998702621
- Output Type
- Journal article
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- Pharmacology & Pharmacy
- Toxicology
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Source: InCites