Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease

Scott B Craig; Glenn C Graham; M A Burnes; M F Dohnt; Lee D Smythe; David B McKay

doi:10.1179/136485909X435058

Back

Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease

Journal article

Peer reviewed

Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease

Scott B Craig, Glenn C Graham, M A Burnes, M F Dohnt, Lee D Smythe and David B McKay

Annals of Tropical Medicine and Parasitology, Vol.103(4), pp.333-341

2009

DOI: https://doi.org/10.1179/136485909X435058

Files and links (1)

url

https://doi.org/10.1179/136485909X435058View

Published Version

Abstract

leptospirosis

haematological markers

In a retrospective study, the laboratory findings from the first blood samples taken following hospital presentation in patients with uncomplicated leptospirosis have been compared with the corresponding data for patients admitted, to a high-dependency medical ward or intensive-care unit, with severe leptospirosis. The aim was to identify those laboratory markers that differentiate the two clinical groups upon initial presentation. Marked differences were observed, in some of the haematological and clinical-chemistry markers, between the patients with severe leptospirosis and those with the uncomplicated disease. Statistically significant differences were found in haemoglobin concentrations, haematocrits, counts of erythrocytes, leucocytes, neutrophils and platelets, and serum concentrations of creatinine, urea, protein and albumin. These markers may therefore be useful in the assessment and early detection of disease severity in patients with suspected leptospirosis. Investigations into the use of albumin treatments, which might significantly improve the clinical care of patients with acute leptospirosis, appear to be justified.

Details

Title: Haematological and clinical-chemistry markers in patients presenting with leptospirosis: a comparison of the findings from uncomplicated cases with those seen in the severe disease
Authors: Scott B Craig (Author) - University of the Sunshine Coast - Faculty of Science, Health and Education
Glenn C Graham (Author) - Queensland Health Forensic and Scientific Services
M A Burnes (Author) - Queensland Health Forensic and Scientific Services
M F Dohnt (Author) - Queensland Health Forensic and Scientific Services
Lee D Smythe (Author) - Queensland Health Forensic and Scientific Services
David B McKay (Author) - University of the Sunshine Coast - Faculty of Science, Health and Education
Publication details: Annals of Tropical Medicine and Parasitology, Vol.103(4), pp.333-341
Publisher: Maney Publishing
Date published: 2009
DOI: 10.1179/136485909X435058
ISSN: 0003-4983
Organisation Unit: School of Science and Engineering - Legacy; University of the Sunshine Coast, Queensland; School of Science, Technology and Engineering
Language: English
Record Identifier: 99449747102621
Output Type: Journal article

Metrics

6 File views/ downloads

602 Record Views

25 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Web Of Science research areas: Parasitology; Public, Environmental & Occupational Health; Tropical Medicine

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites