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Ecology and Evolution - 2023 - Kumar - Genomic signatures of bottleneck and founder effects in dingoes522.67 kB
Published VersionCC BY V4.0, Open Access
Journal article
Genomic signatures of bottleneck and founder effects in dingoes
Ecology and Evolution, Vol.13(9), pp.1-11
2023
Appears in UniSC Supported Open Access Outputs
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UniSC NewsAbstract
Dingoes arrived in Australia during the mid-Holocene and are the top-order terrestrial predator on the continent. Although dingoes subsequently spread across the continent, the initial founding population(s) could have been small. We investigated this hypothesis by sequencing the whole genomes of three dingoes and also obtaining the genome data from nine additional dingoes and 56 canines, including wolves, village dogs and breed dogs, and examined the signatures of bottlenecks and founder effects. We found that the nucleotide diversity of dingoes was low, 36% less than highly inbred breed dogs and 3.3 times lower than wolves. The number of runs of homozygosity (RoH) segments in dingoes was 1.6–4.7 times higher than in other canines. While examining deleterious mutational load, we observed that dingoes carried elevated ratios of nonsynonymous-to-synonymous diversities, significantly higher numbers of homozygous deleterious Single Nucleotide Variants (SNVs), and increased numbers of loss of function SNVs, compared to breed dogs, village dogs, and wolves. Our findings can be explained by bottlenecks and founder effects during the establishment of dingoes in mainland Australia. These findings highlight the need for conservation-based management of dingoes and the need for wildlife managers to be cognisant of these findings when considering the use of lethal control measures across the landscape.
Details
- Title
- Genomic signatures of bottleneck and founder effects in dingoes
- Authors
- Manoharan Kumar (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and EngineeringGabriel Conroy (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationSteven Ogbourne (Author) - University of the Sunshine Coast, Queensland, Centre for BioinnovationKylie Cairns (Author) - UNSW SydneyLiesbeth Borburgh (Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and EngineeringSankar Subramanian (Corresponding Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and Engineering
- Publication details
- Ecology and Evolution, Vol.13(9), pp.1-11
- Publisher
- John Wiley & Sons Ltd.
- Date published
- 2023
- DOI
- 10.1002/ece3.10525
- ISSN
- 2045-7758
- Copyright note
- © 2023 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Organisation Unit
- School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 99971187802621
- Output Type
- Journal article
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