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Journal of Peptide Science - 2024 - Fassolo - Genetically encoded libraries and spider venoms as emerging sources for crop658.69 kB
Published VersionCC BY-NC V4.0, Open Access
Journal article
Genetically encoded libraries and spider venoms as emerging sources for crop protective peptides
Journal of Peptide Science, Vol.30(9), pp.1-9
2024
PMID: 38623834
Appears in UniSC Supported Open Access Outputs
Abstract
Agricultural crops are targeted by various pathogens (fungi, bacteria, and viruses) and pests (herbivorous arthropods). Antimicrobial and insecticidal peptides are increasingly recognized as eco-friendly tools for crop protection due to their low propensity for resistance development and the fact that they are fully biodegradable. However, historical challenges have hindered their development, including poor stability, limited availability, reproducibility issues, high production costs, and unwanted toxicity. Toxicity is a primary concern because crop-protective peptides interact with various organisms of environmental and economic significance. This review focuses on the potential of genetically encoded peptide libraries like the use of two-hybrid-based methods for antimicrobial peptides identification and insecticidal spider venom peptides as two main approaches for targeting plant pathogens and pests. We discuss some key findings and challenges regarding the practical application of each strategy. We conclude that genetically encoded peptide library- and spider venom-derived crop protective peptides offer a sustainable and environmentally responsible approach for addressing modern crop protection needs in the agricultural sector.
Details
- Title
- Genetically encoded libraries and spider venoms as emerging sources for crop protective peptides
- Authors
- Elena Marone Fassolo - University of MilanShaodong Guo - University of the Sunshine Coast, Queensland, Centre for BioinnovationYachen Wang - University of the Sunshine Coast, Queensland, Centre for BioinnovationStefano Rosa - Northeastern UniversityVolker Herzig (Corresponding Author) - University of the Sunshine Coast, Queensland, Centre for Bioinnovation
- Publication details
- Journal of Peptide Science, Vol.30(9), pp.1-9
- Publisher
- John Wiley & Sons Ltd.
- Date published
- 2024
- DOI
- 10.1002/psc.3600
- ISSN
- 1099-1387; 1075-2617
- PMID
- 38623834
- Copyright note
- © 2024 The Authors. Journal of Peptide Science published by European Peptide Society and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
- Organisation Unit
- School of Science, Technology and Engineering; Centre for Bioinnovation
- Language
- English
- Record Identifier
- 991014259202621
- Output Type
- Journal article
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