Journal article
Fostering healthy cognitive ageing in people living with HIV
The Lancet HIV, Vol.12(1), pp.e71-e80
2025
PMID: 39615509
Abstract
Prevalence and incidence of HIV among people aged 50 years and older continue to rise worldwide, generating increasing awareness among care providers, scientists, and the HIV community about the importance of brain health in older adults with HIV. Many age-related factors that adversely affect brain health can occur earlier and more often among people with HIV, including epigenetic ageing, chronic medical conditions (eg, cardiovascular disease), and age-related syndromes (eg, frailty). Extensive dialogue between HIV community leaders, health-care providers, and scientists has led to the development of a multidimensional response strategy to protect and enhance brain health in people ageing with HIV that spans across public health, clinical spaces, and research spaces. This response strategy was informed by integrated ageing care frameworks and is centred on prevention, early detection, and management of brain health issues associated with HIV (eg, neurocognitive disorders), with specific considerations for low-resource or middle-resource countries. A collaborative, international, and data-informed update of the diagnostic criteria for HIV-associated neurocognitive disorders is a cornerstone of the proposed response strategy. The proposed response strategy includes a dynamic, international, online knowledge hub that will provide a crucial community resource for emerging evidence on the brain health of people ageing with HIV.
Details
- Title
- Fostering healthy cognitive ageing in people living with HIV
- Authors
- Lucette A Cysique (Corresponding Author) - St. Michael's HospitalJules Levin - Treatment Action GroupChris Howard - Queensland Positive People (Australia)Jeff TaylorJohn Rule - National Association of People with HIV AustraliaJane Costello - Positive Life NSW (Australia)Jane Bruning - Positive Women Inc (New Zealand)Priscilla Njeri - Positive Life NSW (Australia)Amy B Mullens - University of Southern QueenslandEdwina Wright - Monash UniversityHetta Gouse - University of Cape TownKirstie Daken - University of Southern QueenslandMattia Trunfio - University of California San DiegoHtein Linn Aung - UNSW SydneyReuben N Robbins - Columbia UniversityChristopher M Ferraris - Columbia UniversityJose A Muñoz-Moreno - Hospital Universitari Germans Trias i PujolSteven P Woods - University of HoustonDavid J Moore - University of California San DiegoChristopher Power - University of AlbertaPui Li Wong - University of MalayaKejal Hasmukharay - University of MalayaPrimrose Nyamayaro - University of ZimbabweJaime Vera - Brighton and Sussex Medical SchoolReena Rajasuriar - University of MalayaRobert K Heaton - University of California San DiegoKarl Goodkin - The University of Texas Rio Grande ValleyScott Letendre - University of California San DiegoRonald J Ellis - University of California San DiegoBruce J Brew - St Vincent's Hospital SydneySean B Rourke - University of TorontoNeuroHIV and Aging Advocacy Group
- Publication details
- The Lancet HIV, Vol.12(1), pp.e71-e80
- Publisher
- The Lancet Publishing Group
- Date published
- 2025
- DOI
- 10.1016/S2352-3018(24)00248-0
- ISSN
- 2352-3018; 2405-4704
- PMID
- 39615509
- Grant note
- R21 TW012370 / FIC NIH HHS
- Organisation Unit
- School of Health - Psychology
- Language
- English
- Record Identifier
- 991201542602621
- Output Type
- Journal article
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