Logo image
Back
Flecainide overdose-induced Brugada electrocardiogram pattern
Journal article   Peer reviewed

Flecainide overdose-induced Brugada electrocardiogram pattern

Michael C Y Nam, E-A Karlsen, E Woo, N Dayananda, Kim Greaves and Tony Stanton
QJM: an international journal of medicine, Vol.110(9), p.607
2017
DOI: https://doi.org/10.1093/qjmed/hcx111
url
https://doi.org/10.1093/qjmed/hcx111View
Published Version

Abstract

Medical and Health Sciences flecainide electrocardiogram brugada syndrome overdose
A 64-year-old female with paroxysmal atrial fibrillation presented to the emergency department with atrial fibrillation and rapid ventricular rate (Figure 1A), which was refractory to her usual combination doses of 'pill-in-pocket' metoprolol (25 mg) and flecainide (100 mg). She had a structurally normal heart on recent transthoracic echocardiogram. Upon questioning, the patient received a staggered 600 mg of flecainide in total orally due to a misunderstanding regarding her usual dosing. An electrocardiogram (ECG) obtained at this time revealed widening of the QRS and STdoming in leads V1 and V2, in keeping with a characteristic Type 1 Brugada pattern (Figure 1B). These ECG changes spontaneously resolved within 24 h and sinus rhythm was restored. The patient was reviewed by our local electrophysiologist. There were no features in keeping with high risk Brugada syndrome. Counselling was provided to the patient with regards to avoiding QT prolonging medications, treating pyrexia aggressively, and discontinuing flecainide.

Details

Metrics

2 File views/ downloads
493 Record Views
2 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Web Of Science research areas
Cardiac & Cardiovascular Systems

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

Source: InCites

Logo image