Journal article
Factors associated with the development of depression in chronic non-cancer pain patients following the onset of opioid treatment for pain
Journal of Affective Disorders, Vol.184, pp.72-80
2015
PMID: 26072316
Abstract
Pharmaceutical opioid prescription rates are increasing globally, however knowledge of their long-term effects on mental health, in particular depression remains limited. This study aimed to identify factors associated with the onset of depression post-opioid use that differ to factors associated with depression post-pain.
Participants (N=1418) were a national sample prescribed opioids for chronic non-cancer pain. Age at onset of depression, pain and commencement of opioid medications were collected via structured interview.
Six in 10 (61%) reported lifetime depression; of those, almost half developed depression after pain and after they started opioid medications (48%). Variables associated with post-opioid depression included lower pain self-efficacy and poorer social support, younger onset of opioid use, and difficulties and concerns with opioid medications.
The findings highlight the importance of monitoring for the emergence of mood dysfunction, particularly for those starting opioids for pain at a younger age, and consideration of psychological treatments that address self-efficacy that appears to be associated with post-opioid depression.
•We examined associations with depression post opioid use in people with chronic pain.•Participants were a national sample prescribed opioids for chronic non-cancer pain.•Six in 10 reported lifetime depression, of which 48% had onset post-opioid medication.•Pain self-efficacy, support and medication concerns related to post-opioid depression.•Monitoring mood dysfunction is important when starting opioids.•Psychological treatments that address self-efficacy may be useful.
Details
- Title
- Factors associated with the development of depression in chronic non-cancer pain patients following the onset of opioid treatment for pain
- Authors
- Kimberley Smith (Author) - UNSW AustraliaRichard P Mattick (Author) - UNSW AustraliaRaimondo Bruno (Author) - University of TasmaniaSuzanne Nielsen (Author) - UNSW AustraliaMilton Cohen (Author) - UNSW AustraliaGabrielle Campbell (Author) - UNSW AustraliaBriony Larance (Author) - UNSW AustraliaMichael Farrell (Author) - UNSW AustraliaLouisa Degenhardt (Author) - UNSW Australia
- Publication details
- Journal of Affective Disorders, Vol.184, pp.72-80
- Publisher
- Elsevier BV
- DOI
- 10.1016/j.jad.2015.05.049
- ISSN
- 1573-2517
- PMID
- 26072316
- Organisation Unit
- School of Health and Behavioural Sciences - Legacy; School of Health and Sport Sciences - Legacy; University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99473407402621
- Output Type
- Journal article
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- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Clinical Neurology
- Psychiatry
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Source: InCites