Extended-spectrum β-lactamase producing Escherichia coli in hospital wastewaters and sewage treatment plants in Queensland, Australia

Aycan Gundogdu; Amy V Jennison; Helen V Smith; Helen Stratton; Mohammad Katouli

doi:10.1139/cjm-2013-0515

Back

Extended-spectrum β-lactamase producing Escherichia coli in hospital wastewaters and sewage treatment plants in Queensland, Australia

Journal article

Peer reviewed

Extended-spectrum β-lactamase producing Escherichia coli in hospital wastewaters and sewage treatment plants in Queensland, Australia

Aycan Gundogdu, Amy V Jennison, Helen V Smith, Helen Stratton and Mohammad Katouli

Canadian Journal of Microbiology, Vol.59(11), pp.737-745

2013

DOI: https://doi.org/10.1139/cjm-2013-0515

Files and links (1)

url

https://doi.org/10.1139/cjm-2013-0515View

Published Version

Abstract

sewage treatment plant

Escherichia coli

hospital wastewater

antibiotic-resistant bacteria

We investigated the prevalence of extended spectrum -lactamase (ESBL) producing Escherichia coli in untreated hospital wastewaters and two sewage treatment plants (STPs). A collection of 252 ESBL-producing E. coli isolates from hospital wastewater and STPs were typed and tested for resistance to 17 antimicrobial agents, the presence of integron-associated integrases (intI gene) and ESBL genes. Eighty nine percent (n=176) of the ESBL-producing E. coli strains from hospital waste water were found in more than one sample (common types) with one common type accounting for 35% of isolates, found in all samples. These strains were also resistant to up to 9 non-beta-lactam antibiotics and showed the same pattern of resistance in all samples. More than 73% of the hospital wastewater isolates possessed SHV-type ESBL as opposed to isolates from STPs that carried only CTX-M-type ESBL-genes. The prevalence of intI gene did not differ between isolates from these sources. Certain ESBL-producing E. coli were dominant in hospital wastewaters. These strains possessed -lactamase genes that were different from isolates found in STPs. From a public health point of view, the presence of such a high level of ESBL-producing E. coli strains in hospital wastewaters is of great importance.

Details

Title: Extended-spectrum β-lactamase producing Escherichia coli in hospital wastewaters and sewage treatment plants in Queensland, Australia
Authors: Aycan Gundogdu (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Amy V Jennison (Author) - Queensland Health Forensic and Scientific Services
Helen V Smith (Author) - Queensland Health Forensic and Scientific Services
Helen Stratton (Author) - Griffith University
Mohammad Katouli (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and Engineering
Publication details: Canadian Journal of Microbiology, Vol.59(11), pp.737-745
Publisher: N R C Research Press
Date published: 2013
DOI: 10.1139/cjm-2013-0515
ISSN: 0008-4166
Organisation Unit: University of the Sunshine Coast, Queensland; School of Health and Sport Sciences - Legacy; School of Science, Technology and Engineering; Centre for Bioinnovation
Language: English
Record Identifier: 99449087402621
Output Type: Journal article

Metrics

2 File views/ downloads

751 Record Views

32 Times Cited - Web of Science

See more details

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Web Of Science research areas: Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology; Immunology; Microbiology

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites