Journal article
Exploring associations between early substance use and longitudinal socio-occupational functioning in young people engaged in a mental health service
PLoS One, Vol.14(1), e0210877
2019
Appears in Thompson Institute Research Collection
Abstract
Neuropsychiatric disorders (including substance misuse) are associated with the greatest burden of functional disability in young people, and contributory factors remain poorly understood. Early-onset substance use is one candidate risk factor which may inform functional prognosis and facilitate direction of interventions aiming to curtail impairment. Accordingly, we modelled associations between early-onset use of alcohol, tobacco, cannabis and amphetamine-type stimulants (ATSs) and longitudinal socio-occupational functioning (indexed by the Social and Occupational Functioning Assessment Scale) in an observational cohort presenting to early intervention mental health services. A clinical proforma collated demographic, clinical, and socio-occupational information for up to 60-months from presentation to services in young people aged 17-30. Of the wider cohort (n = 2398), 446 participants were selected with complete alcohol and substance use data. Latent class analysis was used to derive an 'early-onset' (n = 243) and 'later-onset' class (n = 203) based on age of first use of alcohol, tobacco, cannabis and ATSs. Maximum-likelihood multilevel analyses modelled functioning over time in care and tested associations with substance use latent class, age, gender and diagnosis. Membership in the 'early-onset' class (B = -1.64, p = 0.05), male gender (B = -3.27, p&0.001) and psychotic disorder diagnosis (B = -7.62, p<0.001) were associated with poorer functioning at presentation and at least one other time-point. To our knowledge, this is the first study to explore associations of early-onset substance use and longitudinal functioning in a cohort of young people with mental disorders. The identified factors may be useful for directing specific social (e.g. Social Recovery Therapy) or occupational (e.g. Individual Placement and Support) interventions to at-risk individuals, early in illness course.
Details
- Title
- Exploring associations between early substance use and longitudinal socio-occupational functioning in young people engaged in a mental health service
- Authors
- Jacob J Crouse (Author) - University of SydneyKate M Chitty (Author) - University of SydneyFrank Iorfino (Author) - University of SydneyDjango White (Author) - University of SydneyAlissa Nichles (Author) - University of SydneyNatalia Zmicerevska (Author) - University of SydneyAdam J Guastella (Author) - University of SydneyAhmed A Moustafa (Author) - Qatar University, QatarDaniel F Hermens (Author) - University of the Sunshine CoastElizabeth M Scott (Author) - University of SydneyIan B Hickie (Author) - University of Sydney
- Publication details
- PLoS One, Vol.14(1), e0210877
- Publisher
- Public Library of Science
- Date published
- 2019
- DOI
- 10.1371/journal.pone.0210877
- ISSN
- 1932-6203
- Copyright note
- Copyright © 2019 Crouse et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Organisation Unit
- University of the Sunshine Coast, Queensland; Thompson Institute
- Language
- English
- Record Identifier
- 99451367302621
- Output Type
- Journal article
Metrics
36 File views/ downloads
425 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Psychiatry
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites