Exercise Intervention for Bone Metastasis: Safety, Efficacy and Method of Delivery

Huong Duong; Meegan Walker; Michelle Maugham-Macan

doi:10.3390/cancers15061786

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Exercise Intervention for Bone Metastasis: Safety, Efficacy and Method of Delivery

Journal article

Open access

Peer reviewed

Exercise Intervention for Bone Metastasis: Safety, Efficacy and Method of Delivery

Huong Duong, Meegan Walker and Michelle Maugham-Macan

Cancers, Vol.15(6), pp.1-12

2023

DOI: https://doi.org/10.3390/cancers15061786

PMCID: PMC10046160

PMID: 36980672

Appears in Cancer Research Cluster Research Collection

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Abstract

exercise

in-person

bone metastasis

remote

safety

fracture risk

Background: The benefits of exercise for patients with cancer are well established, however, for patients with bone metastases, exercise as adjuvant therapy is underutilised due to concerns for safety, efficacy and other barriers such as the method of delivery. This scoping review explores these barriers by reviewing the results of clinical trials conducted on participants with bone metastases. Methods: A thorough literature search was undertaken using PubMed, Scopus, NIH Clinical Trials and Google Scholar databases. Articles that involved an exercise intervention and patients with bone metastases were included. Data were pooled, charted, analysed and reported according to PRISMA ScR standards. Results: A total of 26 trials were reviewed with interventions that included aerobic and resistance training. Only three serious adverse events occurred, not likely related to bone metastases. Nine trials (34.6%) involved unsupervised exercise sessions. Remote exercise delivery had an average of 80.3% compliance, rivalling in person and mixed supervision. The results of this review reaffirm that exercise helps improve functional capacity, muscle strength, lean mass and cardiovascular function, and is safe in patients with bone metastases irrespective of in person or remote delivery. Conclusions: Exercise therapy, whether delivered in person or remotely, is safe and efficacious for patients with bone metastases.

Details

Title: Exercise Intervention for Bone Metastasis: Safety, Efficacy and Method of Delivery
Authors: Huong Duong (Author) - University of the Sunshine Coast, Queensland, School of Health
Meegan Walker (Author) - University of the Sunshine Coast, Queensland, School of Health - Sports & Exercise Science
Michelle Maugham-Macan (Corresponding Author) - University of the Sunshine Coast, Queensland, School of Health - Biomedicine
Publication details: Cancers, Vol.15(6), pp.1-12
Publisher: MDPI AG
Date published: 2023
DOI: 10.3390/cancers15061786
ISSN: 2072-6694
PMID: 36980672; PMC10046160
Copyright note: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/ 4.0/).
Grant note: SPARK / University of the Sunshine Coast
Organisation Unit: School of Health - Biomedicine; University of the Sunshine Coast, Queensland; Cancer Research Cluster; School of Health - Sports & Exercise Science; Student Services and Engagement; School of Health and Behavioural Sciences - Legacy
Language: English
Record Identifier: 99715098702621
Output Type: Journal article

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