Journal article
Ethnic-specific cut-points for sarcopenia: evidence from black South African women
European Journal of Clinical Nutrition, Vol.69(7), pp.843-849
2015
Abstract
BACKGROUND/OBJECTIVES: Age-related muscle and fat mass (FM) changes are ethnicity specific. We aimed to develop a cut-point for the muscle mass component of sarcopenia for black South African (SA) women, and to assess its predictive value, in comparison to established cut-points, to identify functional ability among older black SA women. SUBJECTS/METHODS: In a cross-sectional study, a sarcopenia cut-point was calculated from dual energy X-ray absorptiometry (DXA)-derived appendicular skeletal muscle mass (ASM) indexes (ASMI) from two young black SA reference groups. The new cutpoint was compared with the most recent Foundation for the National Institutes of Health (FNIH) criteria (ASM o15.02 kg; and ASMBMI o0.512), an internationally accepted cut-point (ASMI o5.5 kg/m2) and a residual method adjusting for FM. All cut-points were then applied to 221 older black women to predict gait speed and handgrip strength. RESULTS: A cut-point of ASMI o4.94 kg/m2 was derived from the young SA reference groups. Using this cut-point, 9.1% of older women were classified as sarcopenic, compared with 16.7-38.7% using other cut-points. The only cut-points that significantly predicted low functional ability (low gait speed and low handgrip strength) in older black women were the new SA cut-point and the FNIH ASM criterion. Multivariate logistic regression models for both these cut-points significantly predicted low handgrip strength (odds ratio (OR) = 3.71, P = 0.007 and OR = 3.42, P = 0.001, respectively) and low gait speed (OR = 9.82, P = 0.004 and OR = 8.71, P = 0.008, respectively). CONCLUSIONS: The new SA cut-point had similar or greater odds of predicting reduced functional ability in older SA women when compared with other internationally accepted cut-points.
Details
- Title
- Ethnic-specific cut-points for sarcopenia: evidence from black South African women
- Authors
- H S Kruger (Author) - North-West University, South AfricaL K Micklesfield (Author) - University of Witwatersrand, South AfricaHattie H Wright (Author) - University of the Sunshine Coast - Faculty of Science, Health, Education and EngineeringL Havemann-Nel (Author) - North-West University, South AfricaJ H Goedecke (Author) - University of Cape Town, South Africa
- Publication details
- European Journal of Clinical Nutrition, Vol.69(7), pp.843-849
- Publisher
- Nature Publishing Group
- Date published
- 2015
- DOI
- 10.1038/ejcn.2014.279
- ISSN
- 0954-3007
- Organisation Unit
- University of the Sunshine Coast, Queensland; School of Health - Nutrition & Dietetics; School of Health and Sport Sciences - Legacy; School of Health and Behavioural Sciences - Legacy
- Language
- English
- Record Identifier
- 99448971502621
- Output Type
- Journal article
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