Electrophysiological correlates of CU traits show abnormal regressive maturation in adolescents with conduct problems

A Sumich; S Sarkar; Daniel F Hermens; K Kelesidi; E Taylor; K Rubia

doi:10.1016/j.paid.2012.06.008

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Electrophysiological correlates of CU traits show abnormal regressive maturation in adolescents with conduct problems

Journal article

Peer reviewed

Electrophysiological correlates of CU traits show abnormal regressive maturation in adolescents with conduct problems

A Sumich, S Sarkar, Daniel F Hermens, K Kelesidi, E Taylor and K Rubia

Personality and Individual Differences, Vol.53(7), pp.862-867

2012

DOI: https://doi.org/10.1016/j.paid.2012.06.008

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Abstract

event-related potential

conduct disorder

callous-unemotional traits

maturation

N200

Callous/unemotional (CU) temperament traits may denote a more severe form of conduct disorder (CD) and have been associated with abnormal cortical thinning. The present study investigated the maturational decline in N200 amplitude, and the association between N200 amplitude and callous/unemotional traits, in adolescents with CD. Twenty adolescent males (aged 10-18. years old) with CD were age-matched to 27 clinical controls with Attention Deficit Hyperactivity Disorder (ADHD) and 30 non-clinical, typically developing controls. Participants completed a visual continuous performance task. As expected, N200 amplitude in response to background stimuli was inversely associated with age in controls (at frontal and temporal brain regions). Similar associations were seen in clinical controls. In contrast, the CD group showed a significant positive correlation between age and the right temporal N200 amplitude. Further, CU traits were positively correlated with N200 amplitude at midline frontal and temporal electrodes, even after covarying for age. These results highlight links between CU traits and abnormal neurodevelopment as indexed by N200 amplitude. This is in line with an impairment or delay in regressive maturational changes such as cortical thinning, as suggested by neuroimaging studies, which may underlie the persistence of certain psychopathic tendencies. © 2012 Elsevier Ltd.

Details

Title: Electrophysiological correlates of CU traits show abnormal regressive maturation in adolescents with conduct problems
Authors: A Sumich (Author) - Nottingham Trent University, United Kingdom
S Sarkar (Author) - Institute of Psychiatry, United Kingdom
Daniel F Hermens (Author) - University of Sydney
K Kelesidi (Author) - Institute of Psychiatry, United Kingdom
E Taylor (Author) - Institute of Psychiatry, United Kingdom
K Rubia (Author) - Institute of Psychiatry, United Kingdom
Publication details: Personality and Individual Differences, Vol.53(7), pp.862-867
Publisher: Pergamon
Date published: 2012
DOI: 10.1016/j.paid.2012.06.008
ISSN: 0191-8869
Organisation Unit: University of the Sunshine Coast, Queensland; Thompson Institute
Language: English
Record Identifier: 99451184802621
Output Type: Journal article

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Web Of Science research areas: Psychology, Social

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