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Published VersionCC BY-NC V4.0, Open Access
Journal article
Effectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: a randomized controlled trial
Clinical Rehabilitation, Vol.34(1), pp.120-131
2020
PMID: 31565952
Abstract
Objective:
To determine the effectiveness of silicone and pressure garments (alone and in combination) in children receiving scar management post-burn.
Design:
Multicentre, parallel-group, randomized controlled trial.
Setting:
Hospital outpatient clinics, colocated research centre, or the participant’s home.
Participants:
Children (0–18 years) referred for burn scar management.
Interventions:
Participants were randomized to (1) topical silicone gel only, (2) pressure garment therapy only, or (3) combined topical silicone gel and pressure garment therapy.
Main measures:
Primary outcomes included scar thickness and itch intensity at the primary end-point of six months post-burn injury. The outcome assessor and data analyst were blinded for scar thickness.
Results:
Participants (N = 153; silicone n = 51, pressure n = 49, combined n = 53) had a median (inter-quartile range) age of 4.9 (1.6, 10.2) years and percent total body surface area burn of 1% (0.5%, 3%) and were 65% male. At six months post-burn injury, intention-to-treat analysis identified thinner scars in the silicone (n = 51 scar sites) compared to the combined group (n = 48 scar sites; mean difference (95% confidence interval) = –0.04 cm (–0.07, –0.00), P = 0.05). No other between-group differences were identified for scar thickness or itch intensity at six months post-burn.
Conclusion:
No difference was identified in the effectiveness of silicone and pressure interventions alone. No benefit to a combined silicone and pressure intervention was identified for the prevention and management of abnormal scarring in children at six months post-burn injury, compared to the silicone or pressure interventions alone.
Details
- Title
- Effectiveness of topical silicone gel and pressure garment therapy for burn scar prevention and management in children: a randomized controlled trial
- Authors
- Jodie Wiseman (Corresponding Author) - The University of QueenslandRobert S Ware - Griffith UniversityMegan Simons - Queensland Children’s HospitalSteven McPhail - Queensland University of TechnologyRoy Kimble - Queensland Children’s HospitalAnne Dotta - Queensland Children’s HospitalZephanie Tyack - Metro South Health
- Publication details
- Clinical Rehabilitation, Vol.34(1), pp.120-131
- Publisher
- Sage Publications Ltd.
- Date published
- 2020
- DOI
- 10.1177/0269215519877516
- ISSN
- 1477-0873; 0269-2155
- PMID
- 31565952
- Copyright note
- © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
- Organisation Unit
- School of Health - Occupational Therapy
- Language
- English
- Record Identifier
- 991113049002621
- Output Type
- Journal article
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- Domestic collaboration
- Web Of Science research areas
- Rehabilitation
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