Journal article
Effect of resistance training on chronic inflammation: a systematic review and meta‐analysis
Translational Sports Medicine, Vol.4(6), pp.900-913
2021
Abstract
Objectives: To determine the pooled effect of resistance training compared with a control, on chronic inflammation in adults through systematic review and meta- analysis (osf.io/xastp).Methods: Intervention trials that assessed resistance training versus control, on peripheral, chronic pro- inflammatory markers [C- reactive protein (CRP), inter-leukin (IL)- 6, and tumor necrosis factor (TNF)- α] in adults were included, from four databases. Random- effect meta- analyses were conducted to calculate stand-ardized mean differences (SMD) in post- intervention values between groups. Meta- regression explored the influence of age, chronic disease, body mass index, progressive resistance training (PRT), and intervention intensity, volume, dura-tion, and “optimal prescription” on the pooled effect.Results: Of 3,186 studies identified, 59 were included. Resistance training re-duced CRP (SMD = −0.28; 95% CI = −0.46, −0.10), but not IL- 6 (SMD = −0.12; 95% CI = −0.31, 0.07) or TNF- α (SMD = −0.07; 95% CI = −0.31, 0.16). Some heterogeneity was explained by interventions of lower intensity (<75% 1RM; 11.47%) or volume between 201 and 300 reps (6.14%).Conclusion: Resistance training instigates small but significant reductions in CRP, but not IL- 6 or TNF- α. Reductions in inflammation caused by resistance training may be influenced by intensity and volume, warranting further investi-gation. Resistance training should be implemented for chronic disease preven-tion or reduced progression, given pooled reductions in CRP.
Details
- Title
- Effect of resistance training on chronic inflammation: a systematic review and meta‐analysis
- Authors
- Grace Laura Rose (Corresponding Author) - University of QueenslandGregore Iven Mielke (Author) - University of QueenslandMadeleine Durr (Author) - University of QueenslandMia Schaumberg (Author) - University of the Sunshine Coast, Queensland, School of Health and Behavioural Sciences - Legacy
- Publication details
- Translational Sports Medicine, Vol.4(6), pp.900-913
- Publisher
- John Wiley & Sons Ltd.
- Date published
- 2021
- DOI
- 10.1002/tsm2.294
- ISSN
- 2573-8488
- Organisation Unit
- School of Health and Behavioural Sciences - Legacy; University of the Sunshine Coast, Queensland; School of Health - Sports & Exercise Science; School of Health - Biomedicine; Cancer Research Cluster
- Language
- English
- Record Identifier
- 99585608202621
- Output Type
- Journal article
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