Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline

Kameshwar Prasad; Reed Siemieniuk; Qiukui Hao; Gordon Guyatt; Martin O'Donnell; Lyubov Lytvyn; Anja Fog Heen; Thomas Agoritsas; Per Olav Vandvik; Sankar Prasad Gorthi; Loraine Fisch; Mirza Jusufovic; Jennifer Muller; Brenda Booth; Eleanor Horton; Auxiliadora Fraiz; Jillian Siemieniuk; Awah Cletus Fobuzi; Neelima Katragunta; Bram Rochwerg

doi:10.1136/bmj.k5130

Back

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline

Journal article

Peer reviewed

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline

Kameshwar Prasad, Reed Siemieniuk, Qiukui Hao, Gordon Guyatt, Martin O'Donnell, Lyubov Lytvyn, Anja Fog Heen, Thomas Agoritsas, Per Olav Vandvik, Sankar Prasad Gorthi, …

British Medical Journal, Vol.363, k5130

2018

DOI: https://doi.org/10.1136/bmj.k5130

Files and links (1)

url

https://doi.org/10.1136/bmj.k5130View

Published Version

Abstract

What is the role of dual antiplatelet therapy after high risk transient ischaemic attack or minor stroke? Specifically, does dual antiplatelet therapy with a combination of aspirin and clopidogrel lead to a greater reduction in recurrent stroke and death over the use of aspirin alone when given in the first 24 hours after a high risk transient ischaemic attack or minor ischaemic stroke? An expert panel produced a strong recommendation for initiating dual antiplatelet therapy within 24 hours of the onset of symptoms, and for continuing it for 10-21 days. Current practice is typically to use a single drug

Details

Title: Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline
Authors: Kameshwar Prasad (Author) - All India Institute of Medical Sciences, India
Reed Siemieniuk (Author) - McMaster University, Canada
Qiukui Hao (Author) - McMaster University, Canada
Gordon Guyatt (Author) - McMaster University, Canada
Martin O'Donnell (Author) - NUI Galway, Ireland
Lyubov Lytvyn (Author) - McMaster University, Canada
Anja Fog Heen (Author) - Innlandet Hospital Trust-division, Norway
Thomas Agoritsas (Author) - McMaster University, Canada
Per Olav Vandvik (Author) - Innlandet Hospital Trust-division, Norway
Sankar Prasad Gorthi (Author) - Kasturba Medical College, India
Loraine Fisch (Author) - University Hospitals of Geneva, Switzerland
Mirza Jusufovic (Author) - Oslo University Hospital, Norway
Jennifer Muller (Author) - Stroke Foundation Australia
Brenda Booth (Author) - Stroke Foundation Australia
Eleanor Horton (Author) - University of the Sunshine Coast - Faculty of Nursing, Midwifery & Paramedicine
Auxiliadora Fraiz (Author)
Jillian Siemieniuk (Author) - Peter Lougheed Hospital, Canada
Awah Cletus Fobuzi (Author) - Cochrane Consumers Group
Neelima Katragunta (Author) - Stanford University, United States
Bram Rochwerg (Author) - McMaster University, Canada
Publication details: British Medical Journal, Vol.363, k5130; 11
Publisher: B M J Group
Date published: 2018
DOI: 10.1136/bmj.k5130
ISSN: 0959-535X; 1756-1833
Organisation Unit: University of the Sunshine Coast, Queensland; School of Nursing, Midwifery and Paramedicine - Legacy
Language: English
Record Identifier: 99451334502621
Output Type: Journal article

Metrics

1 File views/ downloads

398 Record Views

76 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration; International collaboration
Web Of Science research areas: Clinical Neurology

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites