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Dietary Inflammatory Index and Associations with Sarcopenia Symptomology in Community-Dwelling Older Adults
Journal article   Open access   Peer reviewed

Dietary Inflammatory Index and Associations with Sarcopenia Symptomology in Community-Dwelling Older Adults

Corey Linton, Hattie H Wright, Daniel P Wadsworth and Mia A Schaumberg
Nutrients, Vol.14(24), pp.1-12
2022
PMCID: PMC9787040
PMID: 36558478
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Dietary Inflammatory Index and Associations with Sarcopenia Symptomology in Community-Dwelling Older Adults268.69 kBDownloadView
Published Version Open Access CC BY V4.0
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https://doi.org/10.3390/nu14245319View
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Abstract

diet inflammation ageing physical function muscle mass muscle strength UniSC Diversity Area - Life Stages
Low-grade systemic inflammation is a key driver of muscle degeneration in older adults, and diets with pro-inflammatory properties may further contribute to loss of muscle mass, strength and function. Therefore, this research aimed to explore the associations between the inflammatory potential of the diet and measures of sarcopenia symptomology in community-dwelling older adults. Upper (handgrip strength, HGS) and lower extremity (sit-to-stand) muscle strength, physical performance (timed-up-and-go, TUG) and appendicular skeletal muscle mass (ASM) was assessed according to the European Working Group on Sarcopenia in Older People version 2 (EWGSOP2) criteria. Multiple 24-hr dietary recalls were used to calculate the Dietary Inflammatory Index (DII), which was then used to group participants into anti- and pro-inflammatory dietary groups. Multiple linear regression investigated associations between DII, muscle strength, physical performance, and muscle quantity adjusted for age, gender, comorbidities, waist circumference and physical activity. Adults 65–85 years (n = 110, 72.1 ± 4.7 years, 76.4% female) were recruited. One participant was identified with sarcopenia, 35.2% were pre-frail, or frail. More participants with a pro-inflammatory DII score had low muscle quantity than those with anti-inflammatory DII (3.4% vs. 6.4%, x2 = 4.537, p = 0.043) and DII was negatively associated with HGS (β = −0.157, p = 0.016) and ASM (β = −0.176, p = 0.002) which remained significant after adjusting for covariates. In this population, DII was associated with less favorable muscle strength, physical performance, and muscle quantity.

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Nutrition & Dietetics

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#2 Zero Hunger
#3 Good Health and Well-Being
#5 Gender Equality

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