Journal article
Determinants of heterotopic ossification after total hip replacement surgery
Hip International: the journal of clinical and experimental research on hip pathology and therapy, Vol.19(1), pp.41-46
2009
Abstract
The ability of various pre- or peri-operative variables to determine the risk of developing moderate to severe heterotopic ossification (HO ) six to twelve months after surgery was investigated among 407 patients undergoing elective total hip replacement (THR ) surgery and allocated to placebo in a randomised controlled trial evaluating NSA IDs-based prophylaxis for HO . Overall, 11 (30%) of the 37 patients undergoing revision surgery developed moderate to severe HO compared with 58 (16%) of the 370 patients undergoing primary THR ; odds ratio (OR ) 2.3, 95% confidence interval (CI) 1.1 to 4.9. Among patients undergoing primary THR , mutually adjusted analysis of collected independent risk factors demonstrated that receiving a transfusion of red cells or having general as well as epidural or spinal anaesthesia present as indicators of increased risk for developing moderate to severe HO . Patients who have undergone revision surgery have a significantly increased risk of clinically relevant ectopic bone, while among patients who have undergone primary THR surgery, those with indicators of excessive surgical bleeding are also at increased risk of clinically relevant HO .
Details
- Title
- Determinants of heterotopic ossification after total hip replacement surgery
- Authors
- M Fransen (Author) - University of SydneyB Neal (Author) - University of SydneyI D Cameron (Author) - University of SydneyR Crawford (Author) - Queensland University of TechnologyG Tregonning (Author) - Middlemore HospitalJulie Winstanley (Author) - University of the Sunshine Coast - Faculty of Science, Health and EducationR Norton (Author) - University of Sydney
- Publication details
- Hip International: the journal of clinical and experimental research on hip pathology and therapy, Vol.19(1), pp.41-46
- Publisher
- Wichtig Editore Srl
- DOI
- 10.1177/112070000901900108
- ISSN
- 1120-7000
- Organisation Unit
- University of the Sunshine Coast, Queensland
- Language
- English
- Record Identifier
- 99449684002621
- Output Type
- Journal article
Metrics
5 File views/ downloads
701 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- International collaboration
- Web Of Science research areas
- Orthopedics
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites