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Detection and characterization of verotoxin-producing strains among sorbitol non-fermenting Escherichia coli
Journal article   Peer reviewed

Detection and characterization of verotoxin-producing strains among sorbitol non-fermenting Escherichia coli

A Jafari, Mohammad Katouli, F Shokouhi and S Bouzari
Eastern Mediterranean Health Journal, Vol.7(4/5), pp.756-762
2001
url
http://www.emro.who.int/emhj-list/emhj-volume-7-2001/vol7-issue45.htmlView
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Abstract

Microbiology Escherichia coli verotoxin
The presence of genes for verotoxin 1 and 2 (VT1 and 2) among sorbitol non-fermenting Escherichia coli isolates from diarrhoeal cases was assessed using polymerase chain reaction assay. Of 60 (88%) positive isolates, 37 (62%) harboured VT1 and 23 (38%) both VT1 and VT2. In HeLa cell adherence assay, 48 (71%) isolates exhibited mannose-resistant adherence to HeLa cells. Multidrug resistance was observed in 56 (82%) isolates, with ampicillin, chloramphenicol, streptomycin, sulfamethoxazole-trimethoprim and tetracycline pattern being the most common. There were 13 common and 22 single biochemical phenotypes identified. Isolates belonging to common biochemical phenotypes normally had a similar pattern of adherence and VT production, but differed greatly in their pattern of antibiotic resistance, pointing to a high rate of antibiotic-resistance transfer among these isolates.

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