Journal article
Delayed early face processing in bipolar disorder
NeuroReport, Vol.23(3), pp.152-156
2012
Abstract
Bipolar disorder primarily encompasses mood symptom states of depression and mania separated by symptom-free euthymia, and patients also exhibit cognitive deficits that include face processing. However, there is minimal extant event-related potential (ERP) research investigating the time course of these impairments. The aim of the present study was to contribute to a greater understanding of the specific stages of face processing that are impaired in bipolar disorder. Bipolar and age-matched and sex-matched control individuals completed an emotional go/no-go paradigm involving happy and sad face stimuli during ERP acquisition. Amplitudes and latencies of frontocentral P80, N120 and vertex positive potential (VPP) ERP components were analysed in response to 'go' stimuli. Across groups, VPP latencies were reduced in response to sad compared with happy face stimuli. Between groups, individuals with bipolar disorder demonstrated overall increased latencies in P80 and VPP ERP components. Current and previous studies suggest that patients with bipolar disorder exhibit early visual processing deficits, but the present study contributes new evidence of a deficit in the visual P80 ERP. Delayed neural responses may be an ERP correlate of white matter deficits that have previously been identified. Furthermore, implications for early visual impairments may involve behavioural symptoms downstream. Copyright © 2012 Lippincott Williams & Wilkins.
Details
- Title
- Delayed early face processing in bipolar disorder
- Authors
- R Degabriele (Author) - University of SydneyJim Lagopoulos (Author) - University of Sydney
- Publication details
- NeuroReport, Vol.23(3), pp.152-156
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/WNR.0b013e32834f218c
- ISSN
- 0959-4965
- Organisation Unit
- University of the Sunshine Coast, Queensland; Thompson Institute
- Language
- English
- Record Identifier
- 99450063302621
- Output Type
- Journal article
Metrics
363 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Web Of Science research areas
- Neurosciences
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites