Cystic Fibrosis-Related Nontuberculous Mycobacterial Pulmonary Disease

Timothy Baird; Scott Bell

doi:10.1016/j.ccm.2023.06.008

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Cystic Fibrosis-Related Nontuberculous Mycobacterial Pulmonary Disease

Journal article

Peer reviewed

Cystic Fibrosis-Related Nontuberculous Mycobacterial Pulmonary Disease

Timothy Baird and Scott Bell

Clinics in Chest Medicine, Vol.44(4), pp.847-860

2023

DOI: https://doi.org/10.1016/j.ccm.2023.06.008

PMID: 37890921

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Abstract

Cystic fibrosis

Mycobacterium abscessus complex

Mycobacterium avium complex

Non-tuberculous mycobacteria

NTM

Non-tuberculous mycobacteria (NTM) infection is a major cause of morbidity in people with cystic fibrosis (pwCF) with rates of infection increasing worldwide. Accurate diagnosis and decisions surrounding best management remain challenging. Treatment guidelines have been developed to assist physicians in managing NTM in pwCF, but involve prolonged and complex mycobacterial regimens, often associated with significant toxicity. Fortunately, current management and outcomes of NTM in CF are likely to evolve due to improved understanding of disease acquisition, better diagnostics, emerging antimycobacterial therapies, and the widespread uptake of CFTR modulator therapies.

Details

Title: Cystic Fibrosis-Related Nontuberculous Mycobacterial Pulmonary Disease
Authors: Timothy Baird (Corresponding Author) - University of the Sunshine Coast, Queensland, School of Science, Technology and Engineering
Scott Bell (Author) - The University of Queensland
Publication details: Clinics in Chest Medicine, Vol.44(4), pp.847-860
Publisher: Elsevier Inc.
Date published: 2023
DOI: 10.1016/j.ccm.2023.06.008
ISSN: 1557-8216
PMID: 37890921
Organisation Unit: School of Science, Technology and Engineering
Language: English
Record Identifier: 99746797702621
Output Type: Journal article

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