Journal article
Craving mediates the effect of impulsivity on lapse-risk during alcohol use disorder treatment
Addictive Behaviors, Vol.105, pp.1-8
2020
PMID: 32007828
Abstract
Rash impulsiveness, the propensity for approach behaviour despite potential negative consequences, is associated with stronger alcohol craving in patients with Alcohol Use Disorder (AUD). This relationship is poorly understood and implications for treatment response are unexamined. This study explored the relationship between rash impulsiveness, craving, and treatment response among 304 outpatients enrolled in a 12-week abstinence-based Cognitive-Behavioural Therapy (CBT) program for AUD. Assessments were completed pre-and-post treatment, with craving and alcohol consumption monitored at each treatment session. Higher rash impulsiveness predicted more frequent craving over treatment (b = 0.95, 95% CI = 0.40, 1.50). Higher craving was associated with greater lapse-risk (b = 0.04, 95% CI = 0.03, 0.05), with the association between craving and lapse-risk increasing as treatment progressed (b = 0.01, 95% CI = 0.01, 0.02). Craving positively mediated the relationship between rash impulsiveness and lapse-risk (µ = 0.38, 95% CI = 0.10, 0.70). Contrary to hypotheses, the risk of lapse in response to craving was not moderated by rash-impulsiveness. These results suggest that AUD patients with a predisposition for rash impulsiveness are more vulnerable to alcohol craving, and subsequently, poorer treatment outcomes.
Details
- Title
- Craving mediates the effect of impulsivity on lapse-risk during alcohol use disorder treatment
- Authors
- Jason M Coates (Author) - Princess Alexandra HospitalMatthew J Gullo (Author) - Princess Alexandra HospitalGerald F.X Feeney (Author) - Princess Alexandra HospitalRoss Young (Author) - Queensland University of TechnologyGenevieve A Dingle (Author) - Queensland University of TechnologyPaul J Clark (Author) - Princess Alexandra HospitalJason P Connor (Author) - Princess Alexandra Hospital
- Publication details
- Addictive Behaviors, Vol.105, pp.1-8
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.addbeh.2019.106286
- ISSN
- 1873-6327
- PMID
- 32007828
- Organisation Unit
- University of the Sunshine Coast, Queensland; Office of the Deputy Vice-Chancellor (Research and Innovation)
- Language
- English
- Record Identifier
- 99551001902621
- Output Type
- Journal article
Metrics
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- Collaboration types
- Domestic collaboration
- Web Of Science research areas
- Psychology, Clinical
- Substance Abuse
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Source: InCites